ID A0A0M8TMH5_9ACTN Unreviewed; 831 AA.
AC A0A0M8TMH5;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=DEAD/DEAH box helicase {ECO:0000313|EMBL:KOU63598.1};
GN ORFNames=ADK57_22135 {ECO:0000313|EMBL:KOU63598.1};
OS Streptomyces sp. MMG1533.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415546 {ECO:0000313|EMBL:KOU63598.1, ECO:0000313|Proteomes:UP000037741};
RN [1] {ECO:0000313|Proteomes:UP000037741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMG1533 {ECO:0000313|Proteomes:UP000037741};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the helicase family.
CC {ECO:0000256|ARBA:ARBA00008708}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOU63598.1}.
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DR EMBL; LGDG01000213; KOU63598.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M8TMH5; -.
DR STRING; 1415546.ADK57_22135; -.
DR PATRIC; fig|1415546.3.peg.4797; -.
DR Proteomes; UP000037741; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR021904; DUF3516.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR PANTHER; PTHR12131:SF1; ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF12029; DUF3516; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KOU63598.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000037741}.
FT DOMAIN 33..189
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 209..413
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 831 AA; 92817 MW; ADCFA68F0F07ED50 CRC64;
MPPTADPDAL YDAFESWAQE RGLTLYPHQE EALIEAVSGA NVIVSTPTGS GKSMIAAGAH
FAALARDEVT FYTAPIKALV SEKFFELCKI FGTENVGMLT GDASVNSDAP VICCTAEVLA
SIALRDGKHA DVGQVVMDEF HFYAEADRGW AWQIPILELP QAQFILMSAT LGDVSMFEKD
LTRRTGKPTS VVRSATRPVP LSYDYRLTPL TETLTELLET RQAPVYIVHF TQAQAVERAQ
ALMSINMCTR EEKDRIAELI GNFRFTTKFG RNLSRYVRHG IGVHHAGMLP KYRRLVEKLA
QAGLLKVICG TDTLGVGVNV PIRTVLFTAL AKYDGTRVRT LRAREFHQIA GRAGRAGFDT
AGYVVAQAPE HVVENEKALA KAGDDPKKRR KVVRKKAPEG FVGWTDSTFE KLIASDPEPL
TSRFRVTHTM LLSVIARPGN AFEAMRHLLE DNHEPRKQQL RHIRRAIAIY RSLLDGGIVE
KLDEPDAEGR IVRLTVDLQQ DFALNQPLST FALAAFELLD PESPSYALDM VSVVESTLDD
PRQILAAQQN KARGEAVAAM KADGVEYEDR MERLQDVTYP KPLEELLFHA YDTYRKSHPW
VGDHPLSPKS VIRDMYERAM SFTELVSHYE LARTEGIVLR YLASAYKALD HTVPDDLKSE
DLQDLIEWLG EMVRQVDSSL LDEWEQLANP EEMTAEEAQE KADQVKPVTA NARAFRVLVR
NAMFRRVELA ALDHVAELGE MDAEAGWDAD AWGEAMDKYW DEYDDLGTGP DARGPKLLVI
EEEPKNGLWR VRQIFDDPND DHDWGISAEI DLAASDAEGR AIVRVTDVGQ L
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