ID   A0A0M8TW77_9ACTN        Unreviewed;       923 AA.
AC   A0A0M8TW77;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE            EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN   ORFNames=ADK55_00630 {ECO:0000313|EMBL:KOU68366.1};
OS   Streptomyces sp. WM4235.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1415551 {ECO:0000313|EMBL:KOU68366.1, ECO:0000313|Proteomes:UP000037699};
RN   [1] {ECO:0000313|EMBL:KOU68366.1, ECO:0000313|Proteomes:UP000037699}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WM4235 {ECO:0000313|EMBL:KOU68366.1,
RC   ECO:0000313|Proteomes:UP000037699};
RA   Noorani M.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOU68366.1}.
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DR   EMBL; LGDE01000001; KOU68366.1; -; Genomic_DNA.
DR   RefSeq; WP_053674842.1; NZ_LGDE01000001.1.
DR   AlphaFoldDB; A0A0M8TW77; -.
DR   PATRIC; fig|1415551.3.peg.128; -.
DR   OrthoDB; 137117at2; -.
DR   Proteomes; UP000037699; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd14014; STKc_PknB_like; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR031634; PknG_rubred.
DR   InterPro; IPR031636; PknG_TPR.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR24363; SERINE/THREONINE PROTEIN KINASE; 1.
DR   PANTHER; PTHR24363:SF0; SERINE_THREONINE-PROTEIN KINASE DDB_G0277989-RELATED; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   Pfam; PF16919; PknG_rubred; 1.
DR   Pfam; PF16918; PknG_TPR; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:KOU68366.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000037699};
KW   Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527,
KW   ECO:0000313|EMBL:KOU68366.1}; Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          207..496
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   REGION          43..128
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          504..531
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        66..122
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   923 AA;  97341 MW;  62FDDAABC5E7FC29 CRC64;
     MSPSGTACGR PGCPGTYEDM GGGELYCDTC GLAPIGSVAA GAEELVSPPT GMTSAARHGD
     SRGSAGSRGS ERSGSSASAR SSRSSRSSSS RRSVSGRLSR SLSGAASARS VSVRSSGSAP
     SVSGRGRLGA GLVNVPEVPR PDPSAAVLEN PEVPERKRFC SRSDCGAPVG RARGERPGRT
     EGFCTKCGHP YSFVPKLRAG DVVRGQYEVA GCLAHGGLGW VYLAVDRAVS DRWVVLKGLL
     DTGDQDAMEA AISERRFLAE IEHSNIVRIY NFVEHLDQRT GSLDGYIVME YVGGKSLKEI
     ANERRRPDGR RDPLPVEQAC AYGIEALEAL GHLHSRNLLY CDFKVDNAIQ QQDQLKLIDM
     GAVRRMDDDE SAIYGTVGYQ APEVAETGPS VASDLYTVAR TLAVLTFDFQ GYTNVFVDSL
     PDPEHIEVFG RYESFYRLLV RATDPDPGRR FASAQEMADQ LTGVLREVVA LQTGKPRPQL
     STLFGPELHV PDNRLFADEA GAEASRLGAR STAPKGRHGR SGRTAPAPVV AVPPAPVPAP
     TGPVPTGSGP VASVFAGGAP AAAPAAVLRT TATHVSAGAP LLPRQAVAPV APAPGPTLLS
     APVPRQAHGP LHAGIGLAIL DARSAALALP VPLVDPADPN AGFLTGLLAS APADLLGALG
     AAPADSAELR LRELRARLEL GELAVAGQAL LELEVRHPDD WRVVWTRGIA SLAIGDDETA
     ALSFDAIYDA FPGEPAPKLA LGLCAEVLGQ LDNAAEYYRL VWITDPGFVS AAFGLARVQL
     AAGDRAGAVR TLESVPEASI HHTAARVAAV RARLRDRSPE EALLPDLTAA AAQVEALARF
     GLDAERHERL STEVLGSALD WVLSGGRGAD PGRTSLLGSQ LDERGLRFGL ERSYRVLARL
     AQRGEERIEL VERANRFRPR TWV
//