ID A0A0M8UW72_9ACTN Unreviewed; 743 AA.
AC A0A0M8UW72;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=ATP-dependent DNA helicase {ECO:0000313|EMBL:KOV51351.1};
GN ORFNames=ADL00_41075 {ECO:0000313|EMBL:KOV51351.1};
OS Streptomyces sp. AS58.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1519489 {ECO:0000313|EMBL:KOV51351.1, ECO:0000313|Proteomes:UP000037758};
RN [1] {ECO:0000313|EMBL:KOV51351.1, ECO:0000313|Proteomes:UP000037758}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AS58 {ECO:0000313|EMBL:KOV51351.1,
RC ECO:0000313|Proteomes:UP000037758};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOV51351.1}.
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DR EMBL; LGDU01000400; KOV51351.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M8UW72; -.
DR PATRIC; fig|1519489.3.peg.9235; -.
DR Proteomes; UP000037758; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF45; ATP-DEPENDENT DNA HELICASE UVRD2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000037758}.
FT DOMAIN 175..598
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 196..203
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 743 AA; 80865 MW; 1F8398FE1E58911C CRC64;
MRREQEFIDD LYARVDVLRG DVETSVTDAL GQGNTPMQAR LERDILVAER SGLLAALNAV
DGSLCFGRID LASGAGHHIG RIGLRAADAE RTPILIDWRA DVARPFYLAT GHTPMGLRRR
RHITTDGRRV TALHDEILDL GDATRTGHED PTGDAVLLAA LNSARTGRMT DIVQTIQAEQ
DEIIRAPYRG VRVVEGGPGT GKTAVALHRA AYLLYEHREL LARRAVLIVG PNPAFLGYIG
EVLPSLGETG VLLATVGELF PGVRATATDT AEAAAVKGGA AMADVLTAVV RDRQALPDPV
VTIEHDREVL MLDDGLVSVA RERTRAAALP HNAAREHFEG HILNTLTDMV AERIGTDPYD
GSNLLDAVDV TQIRDELADN PEVWSAIDRL WPLLTPQQLV ADFLAAPEAY LSAQDAAAVR
RPVTRAWTVA DVPLLDEAAE LLGEDDRVRR ARAERERETQ VAYAQGVLDV SFASRTYEFE
DKEDSDPDGS EVLSAHDIID AERFAERHEE EDHRSAAERA AADRTWAFGH IIVDEAQELS
PMAWRLLMRR SPTRSMTLVG DPAQTAEAAG VGSWSEILQP YVEDRWHHTR LGVNYRTPAE
IMDLAAAVVR AQVPDFEPPS SVRSTGVHPW VRATGDLPGA VAEAVEELTP AEGRLAVIAP
RDLHRRLAAR LDGVTAGAEP DLTRSVVLLD PRQAKGLEFD SVLVVEPGRY GTSDLYVALT
RATQRLGVLH TGELPKGLAE TVG
//
