ID   A0A0M8UW95_9ACTN        Unreviewed;       399 AA.
AC   A0A0M8UW95;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Hydroxyglutarate oxidase {ECO:0000313|EMBL:KOV51392.1};
GN   ORFNames=ADL00_40750 {ECO:0000313|EMBL:KOV51392.1};
OS   Streptomyces sp. AS58.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1519489 {ECO:0000313|EMBL:KOV51392.1, ECO:0000313|Proteomes:UP000037758};
RN   [1] {ECO:0000313|EMBL:KOV51392.1, ECO:0000313|Proteomes:UP000037758}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AS58 {ECO:0000313|EMBL:KOV51392.1,
RC   ECO:0000313|Proteomes:UP000037758};
RA   Noorani M.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- SIMILARITY: Belongs to the L2HGDH family.
CC       {ECO:0000256|ARBA:ARBA00037941}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOV51392.1}.
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DR   EMBL; LGDU01000399; KOV51392.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M8UW95; -.
DR   PATRIC; fig|1519489.3.peg.9176; -.
DR   Proteomes; UP000037758; Unassembled WGS sequence.
DR   GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:UniProt.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   PANTHER; PTHR43104; L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR43104:SF2; L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   Pfam; PF01266; DAO; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   3: Inferred from homology;
KW   FAD {ECO:0000256|ARBA:ARBA00022827};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000037758}.
FT   DOMAIN          2..375
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
SQ   SEQUENCE   399 AA;  43194 MW;  13A19C8C9E14105B CRC64;
     MSTAYAITRA APGTRVTVLE KEPGPARHQT GRNSGVIHSG IYYRPGSLKA RFAVRGAAEL
     VKFCAEYDIA HAVTGKLIVA TEREELPRLH SLVQRGRENG IPVRELVTAQ IAEYEPEVRG
     LAAIHVGTTG ICDFVGVARR LAEASGAEIR YGARVLRIDR RASLGVAALT ADGSVVRGRV
     LVNCAGLYCD EVARMTGDDP EMRIIPFRGE YYELARPELV RGLVYPVPDP AFPFLGVHLT
     RGIDGGVHVG PNAVPALARE GYAWGVVRPG ETRLALTWPG SWRMARRHWR YGGGEVRRSL
     SRKAFTRAVR RLLPAVTEND LVPAASGVRA QAVLRDGTLV DDFLIREGDR AVHVLNAPSP
     AATASLPIGR EVARRALTVL SGVPDRGGDA AGRPRRRNP
//