ID   A0A0M8V3M1_9ACTN        Unreviewed;       287 AA.
AC   A0A0M8V3M1;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Membrane protein {ECO:0000313|EMBL:KOV57314.1};
GN   ORFNames=ADK64_39120 {ECO:0000313|EMBL:KOV57314.1};
OS   Streptomyces sp. MMG1121.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1415544 {ECO:0000313|EMBL:KOV57314.1, ECO:0000313|Proteomes:UP000037687};
RN   [1] {ECO:0000313|Proteomes:UP000037687}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MMG1121 {ECO:0000313|Proteomes:UP000037687};
RA   Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOV57314.1}.
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DR   EMBL; LGDV01000251; KOV57314.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M8V3M1; -.
DR   STRING; 1415544.ADK64_39120; -.
DR   PATRIC; fig|1415544.3.peg.8515; -.
DR   Proteomes; UP000037687; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.3730.20; -; 1.
DR   InterPro; IPR000620; EamA_dom.
DR   PANTHER; PTHR22911; ACYL-MALONYL CONDENSING ENZYME-RELATED; 1.
DR   PANTHER; PTHR22911:SF137; PROTEIN RARD; 1.
DR   Pfam; PF00892; EamA; 2.
DR   SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000037687};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        32..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        63..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        91..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        116..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        146..165
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        171..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        209..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        240..261
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          5..132
FT                   /note="EamA"
FT                   /evidence="ECO:0000259|Pfam:PF00892"
FT   DOMAIN          146..285
FT                   /note="EamA"
FT                   /evidence="ECO:0000259|Pfam:PF00892"
SQ   SEQUENCE   287 AA;  28320 MW;  A303C4F78318A250 CRC64;
     MAVTAFFALT TSLLWGLADF GGGLLTRRFP ALTVVVVSQA IAATVLGAIV VATGGWSEAG
     PRLWFAFAAG LAGPVALLCF YKALALGPMG VVSPLATLSV AVPVGVGLVL GERPGLLQGT
     GIAVAVTGVV LAGGPQLRGA AVQRQAILLT LVAAMGFGTV FALIAEASTT VTGLFLALFV
     QRLTSVAAGG TALAVSVRRG GRAVPDGGLP WASLPALAFV GLADVAANGT YSVAAQHGPV
     TVAAVLASLY PVVTALAARG FLSERLRAIQ AAGAGLALLG TLLLATG
//