ID A0A0M8VJ87_9ACTN Unreviewed; 329 AA.
AC A0A0M8VJ87;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:KOV66464.1};
GN ORFNames=ADK64_12745 {ECO:0000313|EMBL:KOV66464.1};
OS Streptomyces sp. MMG1121.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415544 {ECO:0000313|EMBL:KOV66464.1, ECO:0000313|Proteomes:UP000037687};
RN [1] {ECO:0000313|Proteomes:UP000037687}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMG1121 {ECO:0000313|Proteomes:UP000037687};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOV66464.1}.
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DR EMBL; LGDV01000118; KOV66464.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M8VJ87; -.
DR STRING; 1415544.ADK64_12745; -.
DR PATRIC; fig|1415544.3.peg.2712; -.
DR Proteomes; UP000037687; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF152; HTH-TYPE TRANSCRIPTIONAL REGULATOR EBGR-RELATED; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000037687};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..48
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 329 AA; 35502 MW; 594411179948D6C5 CRC64;
MAGTSTAVVS YVINNGPRPV APATRERVLA AIKELGYRPD RVAQAMASRR TDLIGLIIPD
ARQPFFGEMA HAVEQAASER GKMVLVGNTD YISEREVHYL RAFLGMRVSG LILVSHALND
LAAAEIDAWD ARVVLLHERP EAIDDVAVVT DDLGGAQLAV RHLLEHGYEY VACMGGTAET
PAVGDPVSDH VEGWKRAMAE AGLPTEGRLF EAPYNRYDAY RVALDVLSGP HRPPAVFCST
DDQAIGLLRA ARELRIDVPG ELAVAGFDDI KEAALADPPL TTVASDRSAM ARAAVDLVLD
DGLRVAGSRR ERLKTFPSRL VLRTSCGCQ
//
