ID   A0A0M8VQD2_9ACTN        Unreviewed;       311 AA.
AC   A0A0M8VQD2;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=[acyl-carrier-protein] S-malonyltransferase {ECO:0000256|ARBA:ARBA00013258};
DE            EC=2.3.1.39 {ECO:0000256|ARBA:ARBA00013258};
GN   ORFNames=ADK64_08995 {ECO:0000313|EMBL:KOV67493.1};
OS   Streptomyces sp. MMG1121.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1415544 {ECO:0000313|EMBL:KOV67493.1, ECO:0000313|Proteomes:UP000037687};
RN   [1] {ECO:0000313|Proteomes:UP000037687}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MMG1121 {ECO:0000313|Proteomes:UP000037687};
RA   Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=holo-[ACP] + malonyl-CoA = CoA + malonyl-[ACP];
CC         Xref=Rhea:RHEA:41792, Rhea:RHEA-COMP:9623, Rhea:RHEA-COMP:9685,
CC         ChEBI:CHEBI:57287, ChEBI:CHEBI:57384, ChEBI:CHEBI:64479,
CC         ChEBI:CHEBI:78449; EC=2.3.1.39;
CC         Evidence={ECO:0000256|ARBA:ARBA00000936};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOV67493.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LGDV01000085; KOV67493.1; -; Genomic_DNA.
DR   RefSeq; WP_053656843.1; NZ_LGDV01000085.1.
DR   AlphaFoldDB; A0A0M8VQD2; -.
DR   STRING; 1415544.ADK64_08995; -.
DR   PATRIC; fig|1415544.3.peg.1916; -.
DR   OrthoDB; 5123945at2; -.
DR   Proteomes; UP000037687; Unassembled WGS sequence.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 2.
DR   InterPro; IPR001227; Ac_transferase_dom_sf.
DR   InterPro; IPR014043; Acyl_transferase.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR   InterPro; IPR049416; VinK-like_small.
DR   PANTHER; PTHR42681; MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR42681:SF1; MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL; 1.
DR   Pfam; PF00698; Acyl_transf_1; 1.
DR   Pfam; PF21124; VinK_C; 1.
DR   SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
PE   4: Predicted;
KW   Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW   Reference proteome {ECO:0000313|Proteomes:UP000037687};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KOV67493.1}.
FT   DOMAIN          8..125
FT                   /note="Malonyl-CoA:ACP transacylase (MAT)"
FT                   /evidence="ECO:0000259|Pfam:PF00698"
FT   DOMAIN          134..195
FT                   /note="Malonyl-CoA-[acyl-carrier-protein] transacylase
FT                   small"
FT                   /evidence="ECO:0000259|Pfam:PF21124"
SQ   SEQUENCE   311 AA;  34322 MW;  42127F052FE5B223 CRC64;
     MAHDTALVFP GMGPVPFAEV GRFMVASPYA RDLVAVADEA LGYSLVDAFR TSAGDYSQAA
     QVAFFVNCLA CAHWARDHLG VEPDIVAGPS FGEKAALAYT GALELPDAVR LTADIARCLE
     EYFAEEHRDI VTLSFVRAPR EGLDTILAEL GEAGEWHEIS CHIDDGFYMI SLSEHRVEWM
     EGRLRAIGSL PLYTMRPPMH ASAFRSLRDK AERDVVSRYT FVDPKLPVVA DQDGRLLHTG
     EELRTMLLDG FDHPMNWPSV TTALKDTGVR RLCVAGPDSL FGRVPCATRN FDVVAAQPRQ
     AMTPRRRTRA A
//