ID   A0A0M8WB68_9NOCA        Unreviewed;       414 AA.
AC   A0A0M8WB68;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Polyketide beta-ketoacyl synthase {ECO:0000313|EMBL:KOV82491.1};
GN   ORFNames=ADL03_24150 {ECO:0000313|EMBL:KOV82491.1};
OS   Nocardia sp. NRRL S-836.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC   Nocardia.
OX   NCBI_TaxID=1519492 {ECO:0000313|EMBL:KOV82491.1, ECO:0000313|Proteomes:UP000037746};
RN   [1] {ECO:0000313|Proteomes:UP000037746}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL S-836 {ECO:0000313|Proteomes:UP000037746};
RA   Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Lipid metabolism; mycolic acid biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00004796}.
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC       synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC       ECO:0000256|RuleBase:RU003694}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOV82491.1}.
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DR   EMBL; LGDY01000106; KOV82491.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M8WB68; -.
DR   STRING; 1519492.ADL03_24150; -.
DR   PATRIC; fig|1519492.3.peg.5184; -.
DR   UniPathway; UPA00915; -.
DR   Proteomes; UP000037746; Unassembled WGS sequence.
DR   GO; GO:0016746; F:acyltransferase activity; IEA:InterPro.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR000794; Beta-ketoacyl_synthase.
DR   InterPro; IPR014031; Ketoacyl_synth_C.
DR   InterPro; IPR014030; Ketoacyl_synth_N.
DR   InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR11712:SF322; POLYKETIDE BETA-KETOACYL SYNTHASE 2-RELATED; 1.
DR   PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR   Pfam; PF00109; ketoacyl-synt; 1.
DR   Pfam; PF02801; Ketoacyl-synt_C; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 2.
DR   PROSITE; PS52004; KS3_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000037746};
KW   Transferase {ECO:0000256|RuleBase:RU003694}.
FT   DOMAIN          3..405
FT                   /note="Ketosynthase family 3 (KS3)"
FT                   /evidence="ECO:0000259|PROSITE:PS52004"
SQ   SEQUENCE   414 AA;  42426 MW;  E6F08E1E5DA96B3C CRC64;
     MTGSAPVVTG LGVIAPSGLG VAEFWPAVRD GHVALAPIGR FEPNPYPVTV AGEVTGFEPA
     GWVEPRIAVQ TDRFTHFALA AADLALRDAA LDPAAVEPFE FGVLTASYSG GVEFGQREIE
     RLWRNGPEHV GPYQSIAWFY AACSGQISIG NGLRGPSGVL VADESGGLDV LAAAGGELRR
     GARAMLVGGA EAPFCPYAMC CQFGLGLLST SGDPATAYQP FTERAVGFAP AEGGAMLVVE
     DAGAAHRRGA AVKAVVAGHC ATYTGRQRFD RSAQGLLRAA TGALAEAGQT PDDVDAVFLD
     AMADPRADAA EAEAVRLLLG ERASRVPVTA PKAGYGRCYA AAAVLDVAAA VLALEHGLVP
     PTPGVDGCRF DLDLVTGAAR PADLRTVLVL SRGVYGGNSA LVLRHPESPI SGGV
//