ID A0A0M8WCH9_9NOCA Unreviewed; 483 AA.
AC A0A0M8WCH9;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=ATP-binding protein {ECO:0000313|EMBL:KOV81387.1};
GN ORFNames=ADL03_28200 {ECO:0000313|EMBL:KOV81387.1};
OS Nocardia sp. NRRL S-836.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1519492 {ECO:0000313|EMBL:KOV81387.1, ECO:0000313|Proteomes:UP000037746};
RN [1] {ECO:0000313|Proteomes:UP000037746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL S-836 {ECO:0000313|Proteomes:UP000037746};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- SIMILARITY: Belongs to the precorrin methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005879, ECO:0000256|RuleBase:RU003960}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOV81387.1}.
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DR EMBL; LGDY01000114; KOV81387.1; -; Genomic_DNA.
DR RefSeq; WP_053736557.1; NZ_LGDY01000114.1.
DR AlphaFoldDB; A0A0M8WCH9; -.
DR STRING; 1519492.ADL03_28200; -.
DR PATRIC; fig|1519492.3.peg.6077; -.
DR OrthoDB; 9804789at2; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000037746; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0030788; F:precorrin-2 C20-methyltransferase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd11645; Precorrin_2_C20_MT; 1.
DR CDD; cd11646; Precorrin_3B_C17_MT; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR InterPro; IPR006363; Cbl_synth_CobJ/CibH_dom.
DR InterPro; IPR012382; CobI/CbiL.
DR InterPro; IPR006364; CobI/CbiL/CobIJ_dom.
DR InterPro; IPR003043; Uropor_MeTrfase_CS.
DR NCBIfam; TIGR01467; cobI_cbiL; 1.
DR NCBIfam; TIGR01466; cobJ_cbiH; 1.
DR PANTHER; PTHR47036; COBALT-FACTOR III C(17)-METHYLTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR47036:SF1; COBALT-FACTOR III C(17)-METHYLTRANSFERASE-RELATED; 1.
DR Pfam; PF00590; TP_methylase; 2.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 2.
DR PROSITE; PS00840; SUMT_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000313|EMBL:KOV81387.1};
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000256|RuleBase:RU003960};
KW Nucleotide-binding {ECO:0000313|EMBL:KOV81387.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000037746};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003960}.
FT DOMAIN 4..213
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
FT DOMAIN 244..448
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
SQ SEQUENCE 483 AA; 51589 MW; 6FC905562A1AAFC3 CRC64;
MTGKLYGVGV GPGDPELVTV KAARLIREAD VIAYHSARHG RSNAKSIAAP YFRDGQIMEQ
LVYPVTTEDT DDYQGEIDAF YEEAAATLAA HLDAGRTVVV LAAGDPFFYG SYMHMHKRLA
HRYEAEVVPG VTSVSGASAV LGTPLVERDE VLTVLPGTLP PAELAARIAD TDCAAILKLG
RTFGNVRQAL EEAGRLDGAW YVERATTGRE RTAKLADVDP ESVPYFSLAL LPSNSRPAQP
GGEVVVVGLG PGHHSWLTPE AKRALESADD LVGYTTYLNR VPERPGQTKH ASHNQVESER
AAFALDLARR GSRVAVVSSG DPGVFAMATA LLEVAAEHPD IPVRVLPGVT AANAVAAKAG
APLGHDYAVI SLSDRLKPWD VIAERLEATA KADLVIAIYN PASKARTHQV ADMRDLLLKH
RSPDTPLIVG RDVGGPEEEI RVLTLGGLDP ATIDMRCLLI IGSSQTVVTD QGVVFTPRRY
PTS
//
