ID   A0A0M8WQB4_9NOCA        Unreviewed;       318 AA.
AC   A0A0M8WQB4;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Methyltransferase {ECO:0000313|EMBL:KOV88303.1};
GN   ORFNames=ADL03_05310 {ECO:0000313|EMBL:KOV88303.1};
OS   Nocardia sp. NRRL S-836.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC   Nocardia.
OX   NCBI_TaxID=1519492 {ECO:0000313|EMBL:KOV88303.1, ECO:0000313|Proteomes:UP000037746};
RN   [1] {ECO:0000313|Proteomes:UP000037746}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL S-836 {ECO:0000313|Proteomes:UP000037746};
RA   Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOV88303.1}.
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DR   EMBL; LGDY01000025; KOV88303.1; -; Genomic_DNA.
DR   RefSeq; WP_053732224.1; NZ_LGDY01000025.1.
DR   AlphaFoldDB; A0A0M8WQB4; -.
DR   STRING; 1519492.ADL03_05310; -.
DR   PATRIC; fig|1519492.3.peg.1117; -.
DR   OrthoDB; 4145676at2; -.
DR   Proteomes; UP000037746; Unassembled WGS sequence.
DR   GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 1.10.287.1350; -; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR016461; COMT-like.
DR   InterPro; IPR001077; O_MeTrfase_dom.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR43712:SF2; O-METHYLTRANSFERASE CICE; 1.
DR   PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR   Pfam; PF00891; Methyltransf_2; 1.
DR   PIRSF; PIRSF005739; O-mtase; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51683; SAM_OMT_II; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:KOV88303.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000037746};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000313|EMBL:KOV88303.1}.
FT   DOMAIN          97..293
FT                   /note="O-methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF00891"
FT   ACT_SITE        228
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ   SEQUENCE   318 AA;  34213 MW;  9939570B0CA4C2AF CRC64;
     MANLVTPMAL RVAVTLGLPD LLAEPRDAGP LAAELDVSPL ALDLLLGHLV TLGVLERTGG
     GYRTTPFGAH LRRDADNGLA NLMDAGTAAG RADLAFVDLL HSVKTGEPAY PLRYGQDFWS
     DLDDHPHLRA AFDGQMAFRI REQLPQVVAG FDWARFATIV DVGGGPGRQL AAILAAHPRV
     RGHLVDLDVA AARTALAPLG ERAQATAGSF FDPLPPGADA YLLFDVLHDW DDEHAERVLR
     RCAEAMPDDG RVLVVEAVGG LGAATEMDLV MLVHFGGRER RVEELEQVAG ASGLVLDRVV
     ELTRSRHLLE FRKGVVTR
//