ID A0A0M8WY01_9ACTN Unreviewed; 329 AA.
AC A0A0M8WY01;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:KOV95091.1};
GN ORFNames=ADL04_22150 {ECO:0000313|EMBL:KOV95091.1};
OS Streptomyces sp. NRRL B-3648.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1519493 {ECO:0000313|EMBL:KOV95091.1, ECO:0000313|Proteomes:UP000037702};
RN [1] {ECO:0000313|EMBL:KOV95091.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL B-3648 {ECO:0000313|EMBL:KOV95091.1};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOV95091.1}.
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DR EMBL; LGDZ01000192; KOV95091.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M8WY01; -.
DR PATRIC; fig|1519493.3.peg.4713; -.
DR Proteomes; UP000037702; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF152; HTH-TYPE TRANSCRIPTIONAL REGULATOR EBGR-RELATED; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000037702};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..48
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 329 AA; 35443 MW; 95AEE4F02147E488 CRC64;
MAGTSTAVVS YVINNGPRPV APATRERVLA AIKELGYRPD RVAQAMASRR TDLIGLIIPD
ARQPFFGEMA HAVEQAASER GKMVLVGNTD YIGEREVHYL RAFLGMRVSG LILVSHALND
LAAAEIDAWD ARVVLLHERP EAIDDVAVVT DDLGGAQLAV RHLLEHGYDY VACMGGTAQT
PAVGDPVSDH VEGWKRAMAE AGLPTEGRLF EAPYNRYDAY RVALEVLSGP HRPPAIFCST
DDQAIGLLRA ARELRIDVPG QLGVAGFDDI KEAALADPPL TTVASDRSAM ARAAVDLVLD
DGLRVAGSRR ERLKTFPSRL VLRTSCGCT
//
