ID   A0A0M8XKJ8_9ACTN        Unreviewed;       201 AA.
AC   A0A0M8XKJ8;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=Ketoreductase (KR) domain-containing protein {ECO:0000259|Pfam:PF08659};
DE   Flags: Fragment;
GN   ORFNames=ADL04_04950 {ECO:0000313|EMBL:KOX07458.1};
OS   Streptomyces sp. NRRL B-3648.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1519493 {ECO:0000313|EMBL:KOX07458.1, ECO:0000313|Proteomes:UP000037702};
RN   [1] {ECO:0000313|EMBL:KOX07458.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL B-3648 {ECO:0000313|EMBL:KOX07458.1};
RA   Noorani M.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC         Evidence={ECO:0000256|ARBA:ARBA00001957};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOX07458.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LGDZ01000044; KOX07458.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M8XKJ8; -.
DR   OrthoDB; 9778690at2; -.
DR   Proteomes; UP000037702; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR013968; PKS_KR.
DR   PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR   PANTHER; PTHR43775:SF51; PHENOLPHTHIOCEROL_PHTHIOCEROL POLYKETIDE SYNTHASE SUBUNIT E; 1.
DR   Pfam; PF08659; KR; 1.
DR   SMART; SM00822; PKS_KR; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000037702}.
FT   DOMAIN          14..196
FT                   /note="Ketoreductase (KR)"
FT                   /evidence="ECO:0000259|Pfam:PF08659"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KOX07458.1"
FT   NON_TER         201
FT                   /evidence="ECO:0000313|EMBL:KOX07458.1"
SQ   SEQUENCE   201 AA;  20481 MW;  F8FBD88EFF2B9ADE CRC64;
     RAAGSGESGL DPDGTVLITG GTGSLAGVLA RHLVTRHGIR HLVLVSRTGL AAEGAPELVA
     ELEALGAESV TVPACDVTDR DAVAALLTGL TGSGPRLTAV VHAAGVFDAG VVGEIEPERL
     ERVFAPKVTA VEHLDELTRE LVPDLDAFLA YSSVSGVFLG AGTGSYGAAN ACMDGLLARR
     RAAGFPARSL AWGLWEQTTG M
//