ID   A0A0M8XVT4_9ACTN        Unreviewed;       964 AA.
AC   A0A0M8XVT4;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   SubName: Full=RNA polymerase subunit sigma-24 {ECO:0000313|EMBL:KOX14102.1};
GN   ORFNames=ADL05_17045 {ECO:0000313|EMBL:KOX14102.1};
OS   Nocardiopsis sp. NRRL B-16309.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Nocardiopsaceae; Nocardiopsis.
OX   NCBI_TaxID=1519494 {ECO:0000313|EMBL:KOX14102.1, ECO:0000313|Proteomes:UP000037694};
RN   [1] {ECO:0000313|Proteomes:UP000037694}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL B-16309 {ECO:0000313|Proteomes:UP000037694};
RA   Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. ECF subfamily.
CC       {ECO:0000256|ARBA:ARBA00010641}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOX14102.1}.
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DR   EMBL; LGEC01000080; KOX14102.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M8XVT4; -.
DR   STRING; 1519494.ADL05_17045; -.
DR   PATRIC; fig|1519494.3.peg.3699; -.
DR   Proteomes; UP000037694; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR   Gene3D; 1.10.1740.10; -; 1.
DR   Gene3D; 1.10.10.1320; Anti-sigma factor, zinc-finger domain; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR041916; Anti_sigma_zinc_sf.
DR   InterPro; IPR039425; RNA_pol_sigma-70-like.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR027383; Znf_put.
DR   NCBIfam; TIGR02937; sigma70-ECF; 1.
DR   PANTHER; PTHR43133:SF58; BLL3014 PROTEIN; 1.
DR   PANTHER; PTHR43133; RNA POLYMERASE ECF-TYPE SIGMA FACTO; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF13490; zf-HC2; 1.
DR   SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR   SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000037694};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        244..265
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        286..307
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          34..102
FT                   /note="RNA polymerase sigma-70 region 2"
FT                   /evidence="ECO:0000259|Pfam:PF04542"
FT   DOMAIN          199..233
FT                   /note="Putative zinc-finger"
FT                   /evidence="ECO:0000259|Pfam:PF13490"
FT   REGION          308..373
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          550..714
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        314..363
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        619..633
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        698..714
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   964 AA;  98756 MW;  E28F2EEDBF6BF0F3 CRC64;
     MVTDADGNHT EVLLGDAEII KRVRGGDTGA YATLYERHAA ASRGLARQLL RGDAEVEDAV
     AEAFTRVLSV IQRGSGPTDS FRPYLLTAVR NAAYDRGRGD KRQVVTDDME SYDSGEPFVD
     PALEGLERSL IARAFLSLPE RWQSVLWHTE IEGIKPAEAA PILGMNANGV AALAYRAREG
     LRQAYLQMHL AGGVAPEACR PALNLLGAYV RGGLSKRDTA KVDSHMDGCA DCREVYAELM
     DVNVGLRGIV LPIFVGAAAA GYLATTPGGA ATGAVWRRMS RRQQQVTAGS AAAAGMAVAI
     ALALVGGPEP LREEPDPVAA PPGQAAPQDD PPPGAPADPP GAPAGAPAAP QPGAPPAADP
     PEAADPPSVL SAVLPPADIP EEELPLEEAP APLFAAGIDP VGALIPGEDG IMVLDVRNIG
     AATVEDVIAL ISLPPGVSMI ADGGAGAAVP AIVGSGDWSC AAEAEGGRCV HTGMAAGEDG
     TQFFDVRVAP DADLGVPARV TVSSGDVTAS VTGERGVSEQ GVAARYATAG RVRTETVGNA
     LMTCVEPESP HWPWPWWESP DAPEAGPQGP PEVPGLGGAE DAGAPDAAPD APDASAAPID
     GGDLRRPPAD PGGSPGVGQE ETPATSEESD SPDADVTPQA PDHESDNDVP AVPLAPDAPS
     APESDGAGEP EEPGTDHPDH APSPVPTSGT EEGGTDGPCA RARAREGDRR DNDHWRMAAL
     DRDWDPTTAS SSSAVWRLPE GGSVRWAGLY FSGGGAPDAA TARIKGPGMA SYTEVAAADT
     RVAELPGYPA YQAFADVTDL VRAQGGGEWW VADVPAREGR AVYAGWSLVV VMEDPEVGSY
     NQAMVLDETG AVFQDPAGIG FPVSGLLPAS VPAVVDVVAW EGDDELDGDR MTLDGRVLVP
     RGPYATGDNA FVGSARGAVG DPMAFGTDVL RAGPVLGRES ELRVVSDGDA VLVGVAVVTA
     PMRT
//