ID   A0A0M8XWE7_9ACTN        Unreviewed;       436 AA.
AC   A0A0M8XWE7;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Sodium:proton antiporter {ECO:0000313|EMBL:KOX14349.1};
GN   ORFNames=ADK66_03880 {ECO:0000313|EMBL:KOX14349.1};
OS   Micromonospora sp. NRRL B-16802.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=1415541 {ECO:0000313|EMBL:KOX14349.1, ECO:0000313|Proteomes:UP000037709};
RN   [1] {ECO:0000313|EMBL:KOX14349.1, ECO:0000313|Proteomes:UP000037709}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL B-16802 {ECO:0000313|EMBL:KOX14349.1,
RC   ECO:0000313|Proteomes:UP000037709};
RA   Noorani M.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOX14349.1}.
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DR   EMBL; LGEB01000002; KOX14349.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M8XWE7; -.
DR   STRING; 1415541.ADK66_03880; -.
DR   PATRIC; fig|1415541.3.peg.810; -.
DR   OrthoDB; 9766690at2; -.
DR   Proteomes; UP000037709; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015293; F:symporter activity; IEA:InterPro.
DR   Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR   InterPro; IPR001991; Na-dicarboxylate_symporter.
DR   InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR   PANTHER; PTHR42865; PROTON/GLUTAMATE-ASPARTATE SYMPORTER; 1.
DR   PANTHER; PTHR42865:SF7; PROTON_GLUTAMATE-ASPARTATE SYMPORTER; 1.
DR   Pfam; PF00375; SDF; 1.
DR   PRINTS; PR00173; EDTRNSPORT.
DR   SUPFAM; SSF118215; Proton glutamate symport protein; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        86..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        148..165
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        186..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        223..243
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        305..324
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          409..436
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   436 AA;  45153 MW;  2C00A5DC6072C89F CRC64;
     MSFGLRKIPF SVQILLGLAL GVAFGFVARS NDLSWLTSTL HTVGSLFIQL LKLAVPPLVF
     TAIVVSVVSL RGVANAARLA VKTLMWFGIT ALIAVSIGIG IGLLVNPGRG VTLDVGAAAP
     PKNTGSWTDF LTGIVPTNPV GAFVEGNVLQ IVFLALVVGA AALLVGDAAE PFVALNRSLL
     EIVQKALWWV IRLAPIGTLG LIGNAVASYG WDLLAPLAKF TTAVYVGCAL VLFVVYPLVL
     ILAGRLNPLR FFAGAWPAIE LAFVSRSSVG TMPVTQRSVE RLGVPREYAS FAVPFGATTK
     MDGCAAIYPA LAAIFVAQVF GVHLGVTDYL LIAFVSVVGS AATAGLTGAI VMLTLTLSTL
     GLPLAGAGLL LAIDPILDMI RTATNVAGQA LVPTVVAARE GTLDRAAYDA AGRRDLTDPE
     PVAETRPDLS PAPAPA
//