ID A0A0M8XYH3_9ACTN Unreviewed; 364 AA.
AC A0A0M8XYH3;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:KOX15637.1};
GN ORFNames=ADL05_14675 {ECO:0000313|EMBL:KOX15637.1};
OS Nocardiopsis sp. NRRL B-16309.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Nocardiopsaceae; Nocardiopsis.
OX NCBI_TaxID=1519494 {ECO:0000313|EMBL:KOX15637.1, ECO:0000313|Proteomes:UP000037694};
RN [1] {ECO:0000313|Proteomes:UP000037694}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL B-16309 {ECO:0000313|Proteomes:UP000037694};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOX15637.1}.
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DR EMBL; LGEC01000073; KOX15637.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M8XYH3; -.
DR STRING; 1519494.ADL05_14675; -.
DR PATRIC; fig|1519494.3.peg.3200; -.
DR OrthoDB; 37081at2; -.
DR Proteomes; UP000037694; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06293; PBP1_LacI-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000037694};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 27..81
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 364 AA; 39395 MW; B1D2FCD21C006064 CRC64;
MRARRPDRSS PSGEPLSTSP RATRRTVGIT EVARHAGVSP GTVSNVLNRP ERVAATTRRK
VEAAIAELDY VRNSSGSSLR SGRSGSVGLL VLDVTNPFFT EVARGVEEEA ATAGLAVVLL
NSAEQQDRQR RNLRLLAEQR AAGAVVMPVD DDLSDLVWLA RQGTAWVALD RGDVSEEVGC
SVSVDNHAGG LAAGRHLIGL GHERITFLTG PFAIEQVRRR HDGLREACAE AHLDPDQAVR
VIEQPQLNAD HGERAVDAVL AGGPRRRPQA VFCANDQLAL GLMKGLGRRG IRVPEDISVV
GYDNVDFADL VHPGLTSVAQ PKFDLGRSAM RLLISELNDP DHRHERTWFT PELVVRGSTA
ARRT
//
