ID   A0A0M8YGB0_9ACTN        Unreviewed;       347 AA.
AC   A0A0M8YGB0;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=IMP dehydrogenase {ECO:0000313|EMBL:KOX24923.1};
GN   ORFNames=ADL06_20075 {ECO:0000313|EMBL:KOX24923.1};
OS   Streptomyces sp. NRRL F-6491.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1519495 {ECO:0000313|EMBL:KOX24923.1, ECO:0000313|Proteomes:UP000037743};
RN   [1] {ECO:0000313|EMBL:KOX24923.1, ECO:0000313|Proteomes:UP000037743}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL F-6491 {ECO:0000313|EMBL:KOX24923.1,
RC   ECO:0000313|Proteomes:UP000037743};
RA   Noorani M.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOX24923.1}.
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DR   EMBL; LGEE01000221; KOX24923.1; -; Genomic_DNA.
DR   RefSeq; WP_053642123.1; NZ_LGEE01000221.1.
DR   AlphaFoldDB; A0A0M8YGB0; -.
DR   PATRIC; fig|1519495.3.peg.4288; -.
DR   OrthoDB; 241504at2; -.
DR   Proteomes; UP000037743; Unassembled WGS sequence.
DR   CDD; cd08287; FDH_like_ADH3; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR42813:SF2; DEHYDROGENASE, ZINC-CONTAINING, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02810)-RELATED; 1.
DR   PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          26..132
FT                   /note="Alcohol dehydrogenase-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08240"
FT   DOMAIN          180..305
FT                   /note="Alcohol dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00107"
SQ   SEQUENCE   347 AA;  35762 MW;  C75DB3F8B69AFA50 CRC64;
     MRATTIHAPF DMRVEDVPDP VIQDPRDVVL RVLRACVCGS DLWAYRGESA RQPGQRIGHE
     FLGVVEEAGD GVRGFRRGDL VVAPFVWSDG TCAYCAEGLQ TSCPRGGFWG SVGSDGGQGE
     AVRVPFADGT LVKLPADAAS DDRLLTALLA LSDVLGTGHH AALGAGVRPG SAVAVVGDGA
     VGLCGVLAAK RLGAERIIAL GRHTARTDIA RAFGATDVVA ERGEAAEAAV RELTGGQGVH
     GVIEAVGTEQ SMRTAVAVAR DGGSIGYVGV PHGSGTGLDL SVMFDRNIAL RGGVAPVRAY
     IPELLPDVLD GTVDPSPVFD LTVGLDGVPG GYKAMDERTA LKVLVKP
//