ID A0A0M8YVC1_9ACTN Unreviewed; 442 AA.
AC A0A0M8YVC1;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Xaa-Pro aminopeptidase {ECO:0000313|EMBL:KOX44142.1};
GN ORFNames=ADL09_26380 {ECO:0000313|EMBL:KOX44142.1};
OS Streptomyces sp. NRRL F-7442.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1519498 {ECO:0000313|EMBL:KOX44142.1, ECO:0000313|Proteomes:UP000037772};
RN [1] {ECO:0000313|EMBL:KOX44142.1, ECO:0000313|Proteomes:UP000037772}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL F-7442 {ECO:0000313|EMBL:KOX44142.1,
RC ECO:0000313|Proteomes:UP000037772};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|ARBA:ARBA00008766}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOX44142.1}.
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DR EMBL; LGEH01000171; KOX44142.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M8YVC1; -.
DR PATRIC; fig|1519498.3.peg.5488; -.
DR Proteomes; UP000037772; Unassembled WGS sequence.
DR GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR CDD; cd01087; Prolidase; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 1.
DR InterPro; IPR007865; Aminopep_P_N.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000994; Pept_M24.
DR PANTHER; PTHR43226; XAA-PRO AMINOPEPTIDASE 3; 1.
DR PANTHER; PTHR43226:SF4; XAA-PRO AMINOPEPTIDASE 3; 1.
DR Pfam; PF05195; AMP_N; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR SMART; SM01011; AMP_N; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000313|EMBL:KOX44142.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Protease {ECO:0000313|EMBL:KOX44142.1}.
FT DOMAIN 33..175
FT /note="Aminopeptidase P N-terminal"
FT /evidence="ECO:0000259|SMART:SM01011"
SQ SEQUENCE 442 AA; 47904 MW; 5B47F6B2EF100E26 CRC64;
MPRLAAMPAF VAYMGQGWGT PDRTAQVVPG AAKAAAEHRA RLAAELPGRT IAVASGRASV
RSNDTFYDFR PDSDFYWLTG CPVENAVLVM DTRAAKDPRS VLYLPRPAQP GDPGFFADAQ
YGELWVGAAP GPRDWARALG HGLEVRPLED LDPALAEGNR DAQVARTLAE LRMIKDDWEI
AQLRTAVDCT VEGFAAVVRE FPTAVAGGGE RWLQGTFDRY ARTYGNGPGY ASIVGSGRHA
ATLHWVRCDG PVGEEEAVLL DMGVETHSYY TADVTRTFPA TGRFSPAQRQ VHDLVERAHR
AGLAAVRPGR DFADFHTAAM DVIAHGLHDW GLLPVSVDEA LSPEGQHHRR WLVCGVGHHL
GLDVHDCARS SYEAYQGAPL APGMVLTVEP GLYFHSHDLA VPPELRGIGV RIEDDVLVTP
EGADVLSDAL PLDATGLENW MR
//
