ID A0A0M8ZPW1_9HYME Unreviewed; 379 AA.
AC A0A0M8ZPW1;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Myeloid differentiation primary response protein MyD88 {ECO:0000313|EMBL:KOX68497.1};
GN ORFNames=WN51_03983 {ECO:0000313|EMBL:KOX68497.1};
OS Melipona quadrifasciata.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC Anthophila; Apidae; Melipona.
OX NCBI_TaxID=166423 {ECO:0000313|EMBL:KOX68497.1, ECO:0000313|Proteomes:UP000053105};
RN [1] {ECO:0000313|EMBL:KOX68497.1, ECO:0000313|Proteomes:UP000053105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0111107301 {ECO:0000313|EMBL:KOX68497.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KOX68497.1};
RA Pan H., Kapheim K.;
RT "The genome of Melipona quadrifasciata.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KQ435922; KOX68497.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M8ZPW1; -.
DR STRING; 166423.A0A0M8ZPW1; -.
DR OrthoDB; 3109068at2759; -.
DR Proteomes; UP000053105; Unassembled WGS sequence.
DR GO; GO:0070976; F:TIR domain binding; IEA:InterPro.
DR GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; IEA:InterPro.
DR GO; GO:0043123; P:positive regulation of canonical NF-kappaB signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR017281; Myelin_different_resp_MyD88.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR15079; MYD88; 1.
DR PANTHER; PTHR15079:SF3; MYELOID DIFFERENTIATION PRIMARY RESPONSE PROTEIN MYD88; 1.
DR Pfam; PF13676; TIR_2; 1.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW Inflammatory response {ECO:0000256|ARBA:ARBA00023198};
KW Reference proteome {ECO:0000313|Proteomes:UP000053105}.
FT DOMAIN 107..238
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
SQ SEQUENCE 379 AA; 43858 MW; B3278CAE9EA6B7FC CRC64;
MTVDLSTVPL VALSIESKYA ISSLLNPPKI LPSENGLPRD WRGLAHFCKL EIERWDILDD
TSKLFERDGE KYLEQLQKSQ TSAEIISNGI DEKILTVGKL RQGLENQYYD AFLLYADEDV
SWATEMLNKL ENKYNLKLCV KDRDLIAGVT FEHEAIMTLI SERCNRLIVI ISSNFLKSPA
NKFFLNYAQA LGIDKQQRKI IPCLYEICKL PPQLRYMFVL DYNRIGLYDF WEKLKDSVQV
ANKVKENANA LLEKDMNNEI ETDEESIKHV ESLEVQTLEL QNSKETLNIK ISNPPEFNNM
YKDNKKYNQF LQWTKKKLSI KGENNKKEDV AITETISLPS IEDLDLLSTS TESIEKKSKI
KFIDKYVKKA HLKKIPVKS
//
