ID   A0A0M8ZW66_9HYME        Unreviewed;      1083 AA.
AC   A0A0M8ZW66;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Thrombospondin type-1 domain-containing protein 4 {ECO:0000313|EMBL:KOX70799.1};
GN   ORFNames=WN51_02223 {ECO:0000313|EMBL:KOX70799.1};
OS   Melipona quadrifasciata.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC   Anthophila; Apidae; Melipona.
OX   NCBI_TaxID=166423 {ECO:0000313|EMBL:KOX70799.1, ECO:0000313|Proteomes:UP000053105};
RN   [1] {ECO:0000313|EMBL:KOX70799.1, ECO:0000313|Proteomes:UP000053105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=0111107301 {ECO:0000313|EMBL:KOX70799.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:KOX70799.1};
RA   Pan H., Kapheim K.;
RT   "The genome of Melipona quadrifasciata.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KQ435851; KOX70799.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M8ZW66; -.
DR   STRING; 166423.A0A0M8ZW66; -.
DR   OrthoDB; 2910701at2759; -.
DR   Proteomes; UP000053105; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:InterPro.
DR   Gene3D; 2.60.120.830; -; 1.
DR   Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 6.
DR   InterPro; IPR013273; ADAMTS/ADAMTS-like.
DR   InterPro; IPR045371; ADAMTS_CR_3.
DR   InterPro; IPR010294; ADAMTS_spacer1.
DR   InterPro; IPR000884; TSP1_rpt.
DR   InterPro; IPR036383; TSP1_rpt_sf.
DR   PANTHER; PTHR13723; ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE; 1.
DR   PANTHER; PTHR13723:SF314; LONELY HEART, ISOFORM A; 1.
DR   Pfam; PF19236; ADAMTS_CR_3; 1.
DR   Pfam; PF05986; ADAMTS_spacer1; 1.
DR   Pfam; PF19030; TSP1_ADAMTS; 6.
DR   PRINTS; PR01857; ADAMTSFAMILY.
DR   SMART; SM00209; TSP1; 6.
DR   SUPFAM; SSF82895; TSP-1 type 1 repeat; 5.
DR   PROSITE; PS50092; TSP1; 5.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053105};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT   DOMAIN          392..472
FT                   /note="ADAMTS/ADAMTS-like cysteine-rich"
FT                   /evidence="ECO:0000259|Pfam:PF19236"
FT   DOMAIN          476..586
FT                   /note="ADAMTS/ADAMTS-like Spacer 1"
FT                   /evidence="ECO:0000259|Pfam:PF05986"
FT   REGION          637..668
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1035..1060
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        637..657
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1083 AA;  120587 MW;  D42745BA7969154A CRC64;
     MSFVHKRDEE LILRDVFLSL CHIFEDNEHK SVQTQALKVP FEVQKWRQSE MQPLSAHCPY
     SVALLRNTSL TELIVGFGVN ELMRYQCDYT TGIKDVLKRH VYLRGISSFE YCAWDEILKI
     LVKYQDIQDI QAYTGHIHIY TCLRNTFRII NSSVHVYSNR MQEEKGKEEE EEVIVVVVVE
     EEEEEEEEVD ERGKSFCVSE QDELKEPRTA FGSNHNPKDG RVRLRGMLNL TGRQLRQYSR
     VAEDEKKLEE DKVGAVLAAG GIPTMKMGFY TSVAGSSSVN EDAERSASQA SILALTMLTA
     ASVSSTHVPD KYPIEKCPNF PEDLRAEQCA KYNGRNYKGE SYDWVPFLDG KLKSLRVPSC
     HFVDNLALKR DVPITVRHFI NCDYCWPAPN SCALNCRAVG ERFYATLEPA VMDGTPCDAP
     NLRGHNAGIS MERTDRWLCV AGQCKSVGCD GVVGSGVTMD ACGVCGGQGK GCRLYEGIFM
     EPILPRGHQP VTTVPKGAMS LNISELRFSS NFLALRDSNG SYILNGPLAY SPSGTYKAAG
     TTLTYQRGDR NRMECILATG PLNDSLHLEI LAQEMNPGVL YKYMMPFGEK PAIAPPLFAT
     GSIDRGNEIP ESDGRVGLMI PVTRISNQKT DLSPTIRNQD RARARERGRK EEMKHSPTTV
     MAGDQPKWKN KKKKRLRFSW KVGLTPCSKE CGGGVQTAIF KCVRENKQVI VNDKRCRNVG
     KPQQPAPLRC NDNPCPPRWR AEPWGECSVT CGTGKRTRKL ECVQELNANL TMRLAAGACV
     QPPDLRSVEA CTKPACANSP ELRHMHSQHD TPRWDVGAWG PRAFYTVFQC STTCGMGTRN
     RTVTCITPGD ACPAFNKPES QKACESAPCV HIGMERRAPW LYSEWSSKCS AECGSGVETR
     RVACADGSEL FCNPKERPET ERQCFGRGSN CDSAKWFTGP WTFCSVSCGV GVQYREVLCV
     ARTNNEFVVL PASNCSDSRP VNEQVCRAGP CTPTWFTSNW SKCSATCGTG VQTRLVRCIL
     EGVGNSNCED AARPSDQQQC DLDPCKKEPS SSSKPPKIAS PHVIAADPNY AYCMYIRFRV
     FAQ
//