ID A0A0M8ZWT5_9HYME Unreviewed; 324 AA.
AC A0A0M8ZWT5;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Protein Wnt {ECO:0000256|RuleBase:RU003500};
GN ORFNames=WN51_03780 {ECO:0000313|EMBL:KOX71666.1};
OS Melipona quadrifasciata.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC Anthophila; Apidae; Melipona.
OX NCBI_TaxID=166423 {ECO:0000313|EMBL:KOX71666.1, ECO:0000313|Proteomes:UP000053105};
RN [1] {ECO:0000313|EMBL:KOX71666.1, ECO:0000313|Proteomes:UP000053105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0111107301 {ECO:0000313|EMBL:KOX71666.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KOX71666.1};
RA Pan H., Kapheim K.;
RT "The genome of Melipona quadrifasciata.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Ligand for members of the frizzled family of seven
CC transmembrane receptors. {ECO:0000256|RuleBase:RU003500}.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498, ECO:0000256|RuleBase:RU003500}.
CC -!- SIMILARITY: Belongs to the Wnt family. {ECO:0000256|ARBA:ARBA00005683,
CC ECO:0000256|RuleBase:RU003500}.
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DR EMBL; KQ435833; KOX71666.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M8ZWT5; -.
DR STRING; 166423.A0A0M8ZWT5; -.
DR OrthoDB; 2874082at2759; -.
DR Proteomes; UP000053105; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR GO; GO:0048699; P:generation of neurons; IEA:UniProt.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd19337; Wnt_Wnt5; 1.
DR Gene3D; 3.30.2460.20; -; 1.
DR InterPro; IPR005817; Wnt.
DR InterPro; IPR043158; Wnt_C.
DR InterPro; IPR018161; Wnt_CS.
DR PANTHER; PTHR12027:SF77; PROTEIN WNT-5; 1.
DR PANTHER; PTHR12027; WNT RELATED; 1.
DR Pfam; PF00110; wnt; 1.
DR PRINTS; PR01349; WNTPROTEIN.
DR SMART; SM00097; WNT1; 1.
DR PROSITE; PS00246; WNT1; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473,
KW ECO:0000256|RuleBase:RU003500};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Reference proteome {ECO:0000313|Proteomes:UP000053105};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687,
KW ECO:0000256|RuleBase:RU003500}.
SQ SEQUENCE 324 AA; 36326 MW; 33924BA24C65D7A9 CRC64;
MIETYDVAAS TICHGLKGLS QGQGKLCQLS VDHMPSVAKG AKFGILECQH QFHDRRWNCS
TISDESVFGP MLRIASRETA FVHAISAAGV VYSISRSCRD GQLSSCGCSR SSRPRDLKRD
WIWGGCGDNL EYGYKFTQAF VDVKERERSF KRGSREQGRS LMNLHNNEAG RRAVIKRSKV
TCKCHGVSGS CSLITCWQQL ASFREIGDFL LDKYDGATEV RVNRRGRLSM RDPRFSLPTA
NDLVYLDESP NYCLPNETLG SLGTHGRICN RTSSGMDGCN LLCCGRGYNT QKTTIRERCE
CKFHWCCYVE CKTCVKSVDI HTCK
//
