ID A0A0M9AAG1_9HYME Unreviewed; 811 AA.
AC A0A0M9AAG1;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Elongation factor Tu {ECO:0000256|RuleBase:RU004061};
GN ORFNames=WN51_09065 {ECO:0000313|EMBL:KOX79263.1};
OS Melipona quadrifasciata.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC Anthophila; Apidae; Melipona.
OX NCBI_TaxID=166423 {ECO:0000313|EMBL:KOX79263.1, ECO:0000313|Proteomes:UP000053105};
RN [1] {ECO:0000313|EMBL:KOX79263.1, ECO:0000313|Proteomes:UP000053105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0111107301 {ECO:0000313|EMBL:KOX79263.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KOX79263.1};
RA Pan H., Kapheim K.;
RT "The genome of Melipona quadrifasciata.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004211}; Single-
CC pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004211}.
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC subfamily. {ECO:0000256|ARBA:ARBA00007249}.
CC -!- SIMILARITY: Belongs to the syntaxin family.
CC {ECO:0000256|ARBA:ARBA00009063, ECO:0000256|RuleBase:RU003858}.
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DR EMBL; KQ435713; KOX79263.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M9AAG1; -.
DR STRING; 166423.A0A0M9AAG1; -.
DR OrthoDB; 167272at2759; -.
DR Proteomes; UP000053105; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0005484; F:SNAP receptor activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd01884; EF_Tu; 1.
DR CDD; cd03697; EFTU_II; 1.
DR CDD; cd03706; mtEFTU_III; 1.
DR CDD; cd15880; SNARE_syntaxin1; 1.
DR CDD; cd00179; SynN; 1.
DR Gene3D; 1.20.5.110; -; 1.
DR Gene3D; 1.20.58.70; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR041709; EF-Tu_GTP-bd.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR033720; EFTU_2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010989; SNARE.
DR InterPro; IPR006012; Syntaxin/epimorphin_CS.
DR InterPro; IPR006011; Syntaxin_N.
DR InterPro; IPR000727; T_SNARE_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004541; Transl_elong_EFTu/EF1A_bac/org.
DR InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR NCBIfam; TIGR00485; EF-Tu; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF03143; GTP_EFTU_D3; 1.
DR Pfam; PF05739; SNARE; 1.
DR Pfam; PF00804; Syntaxin; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00503; SynN; 1.
DR SMART; SM00397; t_SNARE; 1.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47661; t-snare proteins; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
DR PROSITE; PS00914; SYNTAXIN; 1.
DR PROSITE; PS50192; T_SNARE; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Elongation factor {ECO:0000256|ARBA:ARBA00022768,
KW ECO:0000313|EMBL:KOX79263.1}; GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Neurotransmitter transport {ECO:0000256|ARBA:ARBA00022775};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000053105};
KW Transport {ECO:0000256|ARBA:ARBA00022775}.
FT DOMAIN 60..255
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT DOMAIN 714..776
FT /note="T-SNARE coiled-coil homology"
FT /evidence="ECO:0000259|PROSITE:PS50192"
FT COILED 590..628
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 811 AA; 91840 MW; 70FF57BF6AF76D3D CRC64;
MVFSTKMVCS SVLRQAVKQL FLVEHFVKQQ SYGQLRAGSY LSGLITQRFY STKKVFNRDK
PHCNVGTIGH VDHGKTTLTA AITKVLSEME LAKAKQYAEI DNAPEERARG ITINVAHVEY
QTSNRHYGHT DCPGHADYIK NMITGTAQMD GAILVVAATD GSMPQTREHL LLAKQIGISH
IVIFINKVDV ADDEMVELVE MEMRELLTQM GYDGQNIPIV KGSALCALDG TKPEIGRDAI
LKLLEAVDSY IPTPIRELDK PFCLPIENVY SVMGRGTVVS GRLERGKIKK GMDCELIGYN
KLIKTTITGI EMFHKTLEEA EAGDQMGALL RGLKREDIRR GMIMCKPGTM KAYDHLECQI
YMLTTEEGGR VRPMNNMMNG QMFSRTWDCQ AQINLVGKDL VMPGEDTTIV LKLIRPMVCE
KGQRFTIRDS YKTIATGVVA NTLPSLSETE RLELIEVSVF NVKRFENVST LKKQFNDDLL
RSNTSTKESL IYGEAQARKV LNTHAYVYDC QNNNAQSDDD DVADDVSVNV GGPDDFMTEF
FAEVEEIREM IDRIQTNVED VKKKHSAILS APQTDETTNN ETTKIVLVLV AEVKMELEDL
MSDIKKTANK VRAKLKVIEQ NIEQEEHTNK SSADLRIRKT QHSTLSRKFV EVMTEYNRTQ
TDYRERCKGR IQRQLEITGR TTTNEELEEM LEQGNPAVFT QGIIMETQQA KQTLADIEAR
HADIIKLENS IRELHDMFMD MAMLVESQGE MIDRIEYHVE HAVDYVQTAT QDTKKALKYQ
SKARRVSPPQ ITRETIRFSF ASNWSLFVFP T
//
