ID A0A0M9DKJ5_9BACI Unreviewed; 1022 AA.
AC A0A0M9DKJ5;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=ADM90_10390 {ECO:0000313|EMBL:KOY82052.1};
OS Lysinibacillus macroides.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Lysinibacillus.
OX NCBI_TaxID=33935 {ECO:0000313|EMBL:KOY82052.1, ECO:0000313|Proteomes:UP000037977};
RN [1] {ECO:0000313|EMBL:KOY82052.1, ECO:0000313|Proteomes:UP000037977}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 54 {ECO:0000313|EMBL:KOY82052.1,
RC ECO:0000313|Proteomes:UP000037977};
RA Liu B., Wang J., Zhu Y., Liu G., Chen Q., Chen Z., Che J., Ge C., Shi H.,
RA Pan Z., Liu X.;
RT "Genome sequencing project for genomic taxonomy and phylogenomics of
RT Bacillus-like bacteria.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOY82052.1}.
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DR EMBL; LGCI01000006; KOY82052.1; -; Genomic_DNA.
DR RefSeq; WP_053994956.1; NZ_LGCI01000006.1.
DR AlphaFoldDB; A0A0M9DKJ5; -.
DR STRING; 33935.ADM90_10390; -.
DR PATRIC; fig|33935.3.peg.3980; -.
DR OrthoDB; 9809348at2; -.
DR Proteomes; UP000037977; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43047:SF83; HISTIDINE KINASE; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF02518; HATPase_c; 2.
DR Pfam; PF06580; His_kinase; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 2.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 2.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 2.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:KOY82052.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 5..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 340..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 397..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 445..661
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 697..813
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 924..1020
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT MOD_RES 746
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1022 AA; 116117 MW; 0381429DE0BAAD00 CRC64;
MKKNILIIAC IIMLFSIVFF LGNWHYFSDK NPRIVEDGAV TIEAEQLQKN KIVKLDGEWS
FYPNVLIPPQ ASLDSYEDER IAIPVPTKWH KYVQPNEEEQ GLTIGTYHLK VKVPVEGQYG
LYIRTIRQSN RVFMNDIEVG GKGNPSETLS GYQAENDDKY TVFTQSRNNI LDIVIHVTGF
HHPQAGIIYP IEFGTMQAIQ HHYRIKVLTD VLVSVGYVIF GIIYIMSYIQ NRRRKEELFF
GLFAILLGLY MSFINQKVFF MIVPITHALG QLRLQLGSVP LVIMCLTLFI YYMYPQLTKK
RTLYALLVLM GITFFMYAIY NPFTHNTRAT SEEEVTFRKL VYIALNAPVV AYNVWVLIRV
LLKRLEGARY ILIVLIAICC YSVLLAINFI TDIPFDYSEI LLFLLMLFGF VLLLNYRANV
AFIKIQALSE ELLTHNQMKD EFLLKTSHEL RTPLNGIVNL SKSLMEGAQG PLKRAQQEQV
ILIHNITQRL GHLVEDLLFS STHMTGEIRV SPRAVPITVI NEVMTEIQNI MPKNSHVRLI
TEVDKALPNM LTDELRFKQV LYNLLHNAIQ HTKIGEIIVT AHAQQSQMVI RVSDTGAGIP
TQDIEHIFTA FYQVKKQGQK EGLGLGLSIA KNIVEKLDGA IYVTSSLGEG TTFTFTMPLA
TETLVNNEQI FTTMGTQAAT EVLKLNLPLF YKGNDKKILV VDDDHVNIKV LADNLALKGY
TVIAVDNGFD AVAYLKTNEV DCLLIDLMMN GMSGYELCKQ VRKQYDMLEL PIIVLTAIMK
HSDLVLTLQV GANDYLQKPV SMDELLIRIE SLLAVRQSSI DAIEVEMNYL YAQVTPHFVY
NTLNTIIGLS YTNMNDTREA LYCLATYFRA KLNVHYRNSM VPIEEEIELV KAYLYIEKMR
FVDRLTINYD IDESIQLMIP ALSIQPLVEN AVVHGISKKL EGGTIEISVQ RDGQFIRIKI
YDNGVGIPDE KLQQLLNGEG SRIGFMNPLK KFKLMKNASL RLYSEVGKGT TILILLPEGD
GA
//
