ID A0A0M9GSG3_9BACI Unreviewed; 285 AA.
AC A0A0M9GSG3;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Ribosome biogenesis GTPase A {ECO:0000256|ARBA:ARBA00014898, ECO:0000256|PIRNR:PIRNR006230};
GN ORFNames=AAV98_12370 {ECO:0000313|EMBL:KPB04346.1};
OS Bacillus sp. CHD6a.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=1643452 {ECO:0000313|EMBL:KPB04346.1, ECO:0000313|Proteomes:UP000037908};
RN [1] {ECO:0000313|EMBL:KPB04346.1, ECO:0000313|Proteomes:UP000037908}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHD6a {ECO:0000313|EMBL:KPB04346.1,
RC ECO:0000313|Proteomes:UP000037908};
RA Lin W., Liu Y., Zheng Q., Jiao N.;
RT "Genome sequence of Bacillus sp. CHD6a isolated from the shallow-sea
RT hydrothermal environment.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Essential protein that is required for a late step of 50S
CC ribosomal subunit assembly. Has GTPase activity that is stimulated by
CC interaction with the immature 50S ribosome subunit. Binds to the 23S
CC rRNA. Required for the association of ribosomal proteins rplP and rpmA
CC with the large subunit. {ECO:0000256|ARBA:ARBA00025021}.
CC -!- FUNCTION: Required for a late step of 50S ribosomal subunit assembly.
CC Has GTPase activity. {ECO:0000256|PIRNR:PIRNR006230}.
CC -!- SUBUNIT: Interacts with ctc. Interacts with the immature 50S ribosome
CC subunit. 2 molecules of rbgA bind to one 50S subunit.
CC {ECO:0000256|ARBA:ARBA00025856}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR006230}.
CC -!- SIMILARITY: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1
CC subfamily. {ECO:0000256|PIRNR:PIRNR006230}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPB04346.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LBMD01000014; KPB04346.1; -; Genomic_DNA.
DR RefSeq; WP_060665877.1; NZ_LBMD01000014.1.
DR AlphaFoldDB; A0A0M9GSG3; -.
DR STRING; 1643452.AAV98_12370; -.
DR PATRIC; fig|1643452.3.peg.1324; -.
DR OrthoDB; 9779790at2; -.
DR Proteomes; UP000037908; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR CDD; cd01856; YlqF; 1.
DR Gene3D; 1.10.1580.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR030378; G_CP_dom.
DR InterPro; IPR006073; GTP-bd.
DR InterPro; IPR023179; GTP-bd_ortho_bundle_sf.
DR InterPro; IPR019991; GTP-bd_ribosome_bgen.
DR InterPro; IPR016478; GTPase_MTG1.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR03596; GTPase_YlqF; 1.
DR PANTHER; PTHR45782; MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1; 1.
DR PANTHER; PTHR45782:SF4; MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1; 1.
DR Pfam; PF01926; MMR_HSR1; 1.
DR PIRSF; PIRSF006230; MG442; 1.
DR PRINTS; PR00326; GTP1OBG.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51721; G_CP; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|PIRNR:PIRNR006230};
KW GTP-binding {ECO:0000256|PIRNR:PIRNR006230, ECO:0000256|PIRSR:PIRSR006230-
KW 1};
KW Nucleotide-binding {ECO:0000256|PIRNR:PIRNR006230,
KW ECO:0000256|PIRSR:PIRSR006230-1};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517}.
FT DOMAIN 14..180
FT /note="CP-type G"
FT /evidence="ECO:0000259|PROSITE:PS51721"
FT BINDING 58..61
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000256|PIRSR:PIRSR006230-1"
FT BINDING 132..137
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000256|PIRSR:PIRSR006230-1"
FT BINDING 176
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000256|PIRSR:PIRSR006230-1"
SQ SEQUENCE 285 AA; 32155 MW; D3206F2FE02E2645 CRC64;
MTIQWFPGHM AKARRQVTEK LKLIDIVYEL VDARIPVSSR NPMIDEIISN KPRIILLNKA
DMADAKVTRE WLEYFNLPGS STKAIAIDSQ TGKGIQQIAT LSKELLKEKF DKMQSRGIRP
RAIRALIVGI PNVGKSTLIN RLAKKNIAQT GDRPGVTKAQ QWVKVGKELE LLDTPGILWP
KFEDQEVGYR LATTGAIKDT IINLQDIAVF ALRFLTDAYP ERLKERYGLE EIPEDIVELF
DAIGSKRGCK MSGGLIDYDK TAELIIREIR SEKLGKLSLE KPEKL
//
