ID   A0A0M9VXD9_9HYPO        Unreviewed;       473 AA.
AC   A0A0M9VXD9;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=6-hydroxy-D-nicotine oxidase {ECO:0000313|EMBL:KOS23055.1};
GN   ORFNames=ESCO_003776 {ECO:0000313|EMBL:KOS23055.1};
OS   Escovopsis weberi.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Hypocreaceae; Escovopsis.
OX   NCBI_TaxID=150374 {ECO:0000313|EMBL:KOS23055.1, ECO:0000313|Proteomes:UP000053831};
RN   [1] {ECO:0000313|EMBL:KOS23055.1, ECO:0000313|Proteomes:UP000053831}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   de Man T.J., Stajich J.E., Kubicek C.P., Chenthamara K., Atanasova L.,
RA   Druzhinina I.S., Birnbaum S., Barribeau S.M., Teiling C., Suen G.,
RA   Currie C., Gerardo N.M.;
RT   "The genome of the fungus Escovopsis weberi, a specialized disease agent of
RT   ant agriculture.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the oxygen-dependent FAD-linked oxidoreductase
CC       family. {ECO:0000256|ARBA:ARBA00005466}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOS23055.1}.
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DR   EMBL; LGSR01000002; KOS23055.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M9VXD9; -.
DR   STRING; 150374.A0A0M9VXD9; -.
DR   OrthoDB; 1641938at2759; -.
DR   Proteomes; UP000053831; Unassembled WGS sequence.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.465.10; -; 3.
DR   InterPro; IPR012951; BBE.
DR   InterPro; IPR016166; FAD-bd_PCMH.
DR   InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR   InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR   InterPro; IPR006094; Oxid_FAD_bind_N.
DR   PANTHER; PTHR13878; GULONOLACTONE OXIDASE; 1.
DR   PANTHER; PTHR13878:SF91; L-GULONOLACTONE OXIDASE 3; 1.
DR   Pfam; PF08031; BBE; 1.
DR   Pfam; PF01565; FAD_binding_4; 1.
DR   SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR   PROSITE; PS51387; FAD_PCMH; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053831}.
FT   DOMAIN          23..245
FT                   /note="FAD-binding PCMH-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51387"
SQ   SEQUENCE   473 AA;  52230 MW;  42A73C66FE9B3392 CRC64;
     MWPVWQGMTC LPTEKGASST CSLGGYPVYA VNATSVAQIQ AAVNFARNKA LRLVVKNTGH
     DYMGKSVGAG ALSIWTHHLT QIEYIPEYTS SDFRGKAAVA GAGVRTFDIA KIAHENGASL
     VGGQCATVGF AAVQIVTPDG VHRTVNAESH PDLFWAIRGG GASTWGVVTS VTVRLHPRHP
     LTSCWISFHT SAEVSKETFW KGVRAYAENF EHFADAGFYG FTNIRRNHAG YNGSDFSLGI
     EPMLAPNMSM ESFDEVTRPF FDQLAALGIP FQAERRYFDS FHEGWAEIWP SEILVVAEPL
     DTPGSRLFPR EVWTDPEGLT AILDTFRNIS ELGYDVTGFL IAPQNPFNVD NAVSPALRHA
     LGYFSTSVEF PGNATSEHKA AAQEELMRNI LDPWREVAPS SKFGGSYLNE ANPMEPFWQD
     DLYGGNYPRL LEIKRKYDPN SLFYAVTGVG SEEWEVRSTE QGFRTQNGRL CRV
//