ID   A0A0M9WAF4_9EURO        Unreviewed;      1115 AA.
AC   A0A0M9WAF4;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=DUF726 domain protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=ACN38_g11831 {ECO:0000313|EMBL:KOS37383.1};
OS   Penicillium nordicum.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=229535 {ECO:0000313|EMBL:KOS37383.1, ECO:0000313|Proteomes:UP000037696};
RN   [1] {ECO:0000313|EMBL:KOS37383.1, ECO:0000313|Proteomes:UP000037696}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DAOMC 185683 {ECO:0000313|EMBL:KOS37383.1,
RC   ECO:0000313|Proteomes:UP000037696};
RA   Nguyen H.D., Seifert K.A.;
RT   "Genome sequencing of Penicillium nordicum.";
RL   Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the TMCO4 family.
CC       {ECO:0000256|ARBA:ARBA00009824}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOS37383.1}.
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DR   EMBL; LHQQ01000324; KOS37383.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M9WAF4; -.
DR   OrthoDB; 8526at2759; -.
DR   Proteomes; UP000037696; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProt.
DR   GO; GO:0072330; P:monocarboxylic acid biosynthetic process; IEA:UniProt.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR007941; DUF726.
DR   PANTHER; PTHR17920:SF24; LIPASE MIL1-RELATED; 1.
DR   PANTHER; PTHR17920; TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4; 1.
DR   Pfam; PF05277; DUF726; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000037696};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        539..570
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        582..604
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..212
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          395..450
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          933..953
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          986..1041
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..17
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        25..46
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        66..90
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        92..109
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        165..186
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        399..422
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        993..1008
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1012..1026
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1115 AA;  121898 MW;  0C4DD5C793BCA258 CRC64;
     MTATSGVTVD TSDHPIPSPP NATNPSQQEP QSKGDSPTNQ NEKETEGPLP PTLASEPAAE
     SAKQDPPASD EVDDFGLPIR ARRPDPTPRE TPEGENASQN IQNVAVSSGY SDALKEEKEP
     ELQQGKLDSG APEPVNSNNT EERGKSAEAQ DNSAPPEYSP AAGPHAQPRT STSKQRTAQV
     SEWSHQRLAQ PDAHHPESEE SDAEPDEWQS MPALGEFDYY DDYGRLVARG AKEEGDEAVY
     QGLGGAGRGY TRVQLDEDAQ SATSLDDDTS YLFRETGDNS AGLVGEEMRD SISQLQATKD
     LLNETQKIAY VGVVRLAIHS MNHDLASIAT TKSTRKTMQK ASDASRKWGQ AIMGRVYAHM
     DINSAEQIMI EQLAEHGVQP EDLVPPLMQN ARVKNPMAES EPKTSTSSQK LDSPSRISAE
     TESSELDPPP PYQAHETEEP PEVKMPSEMP TSDRIDIDLR WTVLCDLFLV LIANSAYDAR
     SRTLLERVGA ALDVTWLQIS RFEKRVTDSL EMQEQAEKEN WDESDHMEKR RKMALKRKYM
     IMGLATVGGG LVIGLSAGLL APVIGAGLAA GFTTVGISGT SAFLGGAGGT ALIASSATLG
     GSTIGMRASK RRMGAVQTFE YRPLHNNKKV NLIVTVSGWM TGKVDDVRLP FSTVDPIMGD
     IYSVLWEPEM LRSMGDTINI LATEALTQGL QQVLGSTVLM ALMASLQLPL VLTKLAYLID
     NPWIVSLARA NSAGLVMADS LRERNLGNRP ITLLGFSLGA RVIFSCLKEL AEKGAHGLIQ
     NVYLFGSPVV ANKDEYLKAR SVVSGRFVNG YATNDWILGY LFRATSGGIM KVAGLAAVEG
     IPGIENFNIT ALVNGHMDYR TAMPRILREV GWEVLEDEFA EIEDPDPDNH AERQRELIRE
     IDEARREAEA KPEKKRFGLF KRGKMAEKKK WETYDVDQNT APRDSSEPES APGTVLFDIE
     AIRAELHSEA IEIKELESTM PLMKLDLNAP SEPQPAQPSP PVPKRPKTPN ELPAVSRTSS
     LPPPASAQYS PHGPNEITPV PKHEDMEMTF DTSFHDFPRY QHDEIHSRPE LRTASTMPTM
     PTVGSSALGA MAMEPNAWAD HDQGHRDGEI SMTFE
//