ID A0A0M9WFH3_9EURO Unreviewed; 1059 AA.
AC A0A0M9WFH3;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=ACN38_g6256 {ECO:0000313|EMBL:KOS42855.1};
OS Penicillium nordicum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=229535 {ECO:0000313|EMBL:KOS42855.1, ECO:0000313|Proteomes:UP000037696};
RN [1] {ECO:0000313|EMBL:KOS42855.1, ECO:0000313|Proteomes:UP000037696}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DAOMC 185683 {ECO:0000313|EMBL:KOS42855.1,
RC ECO:0000313|Proteomes:UP000037696};
RA Nguyen H.D., Seifert K.A.;
RT "Genome sequencing of Penicillium nordicum.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOS42855.1}.
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DR EMBL; LHQQ01000095; KOS42855.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M9WFH3; -.
DR STRING; 229535.A0A0M9WFH3; -.
DR OrthoDB; 57056at2759; -.
DR Proteomes; UP000037696; Unassembled WGS sequence.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47835; HFM1, ATP DEPENDENT DNA HELICASE HOMOLOG; 1.
DR PANTHER; PTHR47835:SF2; SEC63 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF02889; Sec63; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00973; Sec63; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022806};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022806};
KW Reference proteome {ECO:0000313|Proteomes:UP000037696}.
FT DOMAIN 1..174
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 580..633
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 673..699
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 734..1018
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 593..631
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 750..779
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 794..809
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 933..962
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 963..977
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 999..1018
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1059 AA; 117963 MW; AA306A12C475B71F CRC64;
MVFCCTRNSS LATAKELARL FTLTNPFARL WNGPKKRLEA HNEDLKTTLP AGVAFHHAGL
GPADRHTVET GFREGNINVI CCTSTLAVGI NLPCHSVIIK NTASWQDGGF KEYSDLEMMQ
MLGRAGRPQF DDSATAVILT RKERVAHYER LVQGSESLES CLHLNLIDHL NAEVGLGNIA
DVESAVKWLG GTFLFVRLRR NPTHYKLKEG ANQEDEDQLL RDICEKDISL LQKYGLVEGE
SLRSTQFGEA MARYYIQFET MKVLLSLKPK ATLSEILNVI AQGEEFREIR LKAGEKSLYR
EINRDPGIRF PIKVDLALPA HKISLLLQSE LGAIEYPDND QLQKHKFNFQ QDKSLVFAHA
NRLIRCLLDC QIARGDSITI LNALELARSL GAKVWDHSPL QMKQIEQVGI VTVRKLAAAG
ITSIEVLECA EAHQIEMVLS KNPPFGSKLL SRLKEFPKLR VSVKMLGKEV KVDCVNVRFK
AEVAFMNDKT PTYFQHHPVY VCCLIERSDG HMIDFRRTSA GKLQEKFEIE LTAELTSSEH
VIVCHVMCDE IAGTSRQAEL RPNLPSHLFA ALRDMNTNAQ NTETSNLPSR HPERNLNSKD
AEKPKTNTSR PHGRDMTSIK TKSRQSVDDF DGDDLQLDDF LVANEPRGKA KESTKPQSRQ
VDGFDDIDWF SIDATPPRPA KGVPKVSNTR EDDWGVDLDE PEDEYEPVRL ANGKWACNHK
CRDKTSCKHF CCREGLEKPP KPPKRTIPAT QKEGSLNQLT ISASITKAPT SNSSSKKQVA
KKRVMGPKND GHVSKMKMST SQAGKKDLSQ EMSVLSERDK NVPSYKRKLE KSPAPLSSDY
GDENFDDLPS PSRLLGSSRG SGFATWVSPV ADDQAENKIT DVPAIESKHT ETDPSHSASQ
SDFLQLDQMK PSNPKPEHEI IEIPDDTPPD SEMTITKDPS AKQGTLPLTT KADQPSTLKR
KASQDVTRTE HKKQVKQRPF VSALQVHASN SLDDEPPLSP EQPVSPISPA SPTSPVPPVP
LVPPIPAVPV IGGQMDLNTT WDNNGIDLLD EFKDIIKFI
//
