ID   A0A0M9YMY1_9ACTN        Unreviewed;       374 AA.
AC   A0A0M9YMY1;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Hydrolase {ECO:0000313|EMBL:KOU53498.1};
GN   ORFNames=ADK55_15450 {ECO:0000313|EMBL:KOU53498.1};
OS   Streptomyces sp. WM4235.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1415551 {ECO:0000313|EMBL:KOU53498.1, ECO:0000313|Proteomes:UP000037699};
RN   [1] {ECO:0000313|EMBL:KOU53498.1, ECO:0000313|Proteomes:UP000037699}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WM4235 {ECO:0000313|EMBL:KOU53498.1,
RC   ECO:0000313|Proteomes:UP000037699};
RA   Noorani M.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOU53498.1}.
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DR   EMBL; LGDE01000192; KOU53498.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M9YMY1; -.
DR   PATRIC; fig|1415551.3.peg.3385; -.
DR   Proteomes; UP000037699; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd07725; TTHA1429-like_MBL-fold; 1.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR23131; ENDORIBONUCLEASE LACTB2; 1.
DR   PANTHER; PTHR23131:SF0; ENDORIBONUCLEASE LACTB2; 1.
DR   Pfam; PF00753; Lactamase_B; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:KOU53498.1};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000037699}.
FT   DOMAIN          54..284
FT                   /note="Metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|SMART:SM00849"
SQ   SEQUENCE   374 AA;  40749 MW;  5360FC19420154AE CRC64;
     MGDYWNKFSL SCAGGRTTAR TAGRQGALVT PQVTDHGGGV WGVKVPIPDN PLGHTLVHVL
     DTDRGPVLVD TGWDDPESWD TLVAGLDALG IAMADVHGVV ITHHHPDHHG LSGRVREASG
     AWIAMHAADT EVVVRTRSAE PGVWFDYMSE KLAVAGAPEE HIAPLRAART SGRLRTLPGL
     HAAVPDREIV PGELLPLAGR RLRAIWTPGH TPGHVCLHLE EAHPAGLPGN GRLFSGDHLL
     PGISPHIGLY EDPSEHRVTD PLGDYLDSLE RVGRLEPAEV LPAHQHPFTD APGRVRELLD
     HHEERLTGLW GLLATPLTPW ELAERMEWNR PWEQIPYGSR NIAVSEAEAH LRRLVKQGRA
     EPVPGSDPVT YRAL
//