ID   A0A0N0ADX6_9ACTN        Unreviewed;       744 AA.
AC   A0A0N0ADX6;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Membrane protein {ECO:0000313|EMBL:KOX02436.1};
GN   ORFNames=ADL04_12405 {ECO:0000313|EMBL:KOX02436.1};
OS   Streptomyces sp. NRRL B-3648.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1519493 {ECO:0000313|EMBL:KOX02436.1, ECO:0000313|Proteomes:UP000037702};
RN   [1] {ECO:0000313|EMBL:KOX02436.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL B-3648 {ECO:0000313|EMBL:KOX02436.1};
RA   Noorani M.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the YccS/YhfK family.
CC       {ECO:0000256|ARBA:ARBA00043993}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOX02436.1}.
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DR   EMBL; LGDZ01000119; KOX02436.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N0ADX6; -.
DR   PATRIC; fig|1519493.3.peg.2659; -.
DR   Proteomes; UP000037702; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR049453; Memb_transporter_dom.
DR   InterPro; IPR032692; YccS_N.
DR   PANTHER; PTHR30509:SF9; INNER MEMBRANE PROTEIN YCCS; 1.
DR   PANTHER; PTHR30509; P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT-RELATED; 1.
DR   Pfam; PF12805; FUSC-like; 1.
DR   Pfam; PF13515; FUSC_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000037702};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        46..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        94..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        120..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        168..188
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        396..420
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        440..458
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        488..505
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        517..537
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          101..241
FT                   /note="Integral membrane protein YccS N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12805"
FT   DOMAIN          406..529
FT                   /note="Integral membrane bound transporter"
FT                   /evidence="ECO:0000259|Pfam:PF13515"
FT   REGION          710..744
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        715..729
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   744 AA;  79268 MW;  4673C3F9A2AFE1B6 CRC64;
     MPHHHQAEAT RRGVPARLTS VTWLRAFGEV VRSGLTIEET RLEPLLALRT AAGVAIVIGP
     ALWLISPAYA ASAALGAYSA GGATFQRTWR PRKVIALGAG AGLALSTFVG YLAAGRLVTF
     LPLLAVWAFA AGMAWAVGST AGIVAATTVG SMLVTITLPT SVGRALEHAG VIALGGVVQA
     VLILLFPVRR WGAHRDALAD ALAAVADYAR RLRHDPTAPF DPEPLMTARD AAAVTPSQAR
     TRPPVLHGPR GLAERIRPVV AALADPDVGA PAEGPGRDRA RELLNAAADV LDAAARSIRL
     GTPVGVPPGS ADVLRVDEEH EVLEGPARQA AERLVELLGE ALEIAGSGCA RERTPIPPGP
     AGARFLVRPT MLRLVPVVVR AVRRELRRDS PVFRHAVRLA AVATLGYLIA ARLPLGHGYW
     APIASVMVMR PDFHRTYARA VARLAGTLAG VGLATGMVRA LGPDAHVFGA LAVVSAGLSY
     TVIRTGYAYS QCFTAAYVVF LLGMGGQTWE QTVPERVVLT LLGGSLAMLA YVVFPAWETP
     RLPGRLADWL AANGRYAAAV LRSYAEPSRE HRADMRRALL ASREARAAWQ EAYDQARQEP
     VRPRGLTMRE AQDAQEALKR FGRAAMLMES HVPRADGRFS PEAERFAEAL EADTAQAADA
     VREHRNPDWG HVEEALRAWE GAAGDRSPVV RRGAELQKRA LEDLATAVSR TPLERDVGSA
     REDQRVRATL AAEGDGSGPA HREG
//