ID   A0A0N0AE15_9ACTN        Unreviewed;       427 AA.
AC   A0A0N0AE15;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=3-hydroxyacyl-CoA dehydrogenase {ECO:0000313|EMBL:KOX03084.1};
GN   ORFNames=ADL04_11545 {ECO:0000313|EMBL:KOX03084.1};
OS   Streptomyces sp. NRRL B-3648.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1519493 {ECO:0000313|EMBL:KOX03084.1, ECO:0000313|Proteomes:UP000037702};
RN   [1] {ECO:0000313|EMBL:KOX03084.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL B-3648 {ECO:0000313|EMBL:KOX03084.1};
RA   Noorani M.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the peptidase M14 family.
CC       {ECO:0000256|ARBA:ARBA00005988}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOX03084.1}.
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DR   EMBL; LGDZ01000118; KOX03084.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N0AE15; -.
DR   PATRIC; fig|1519493.3.peg.2472; -.
DR   Proteomes; UP000037702; Unassembled WGS sequence.
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR000834; Peptidase_M14.
DR   PANTHER; PTHR11705:SF91; CARBOXYPEPTIDASE A1 (PANCREATIC)-RELATED; 1.
DR   PANTHER; PTHR11705; PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B; 1.
DR   Pfam; PF00246; Peptidase_M14; 1.
DR   SMART; SM00631; Zn_pept; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000037702}.
FT   DOMAIN          20..255
FT                   /note="Peptidase M14 carboxypeptidase A"
FT                   /evidence="ECO:0000259|SMART:SM00631"
SQ   SEQUENCE   427 AA;  46206 MW;  A88A967BD1E2484C CRC64;
     MGERSRADKS GVSPLPELRY PSVPELVAAA EALAAQEPGL CALRQVGVSR AGRPLHLLSV
     GHARRAVLVV AGAHANEPAG GSTLRVLAER VLSERELRAG TSWHFLLCAD PDGASLHVTP
     APRSLLDYHL GFYRPTGAEQ PEWSPSVLPP DRLPPETRAL TGVIDELRPY LQVTLHGTDL
     GGSWVQLTKD VPGLAEPFAK SAAELHIPVE TGASDAAGWP ASGPGVHVMP GPESGVAYPS
     MPDDARHSTW YHAHRYGGLT AVVEVPMWAS DLVDDPAPHP APAAAMRRLA VRLLRDAREV
     ERILADSLPR LEGVDGPLLR AARWALELIP GLAEDWTHTS PAGTTMAYVG SVDAFGRRLP
     LRAAAMLLRV LRETDDRAAP RLEQLVATWC DAFSERFRAR WVPLEHQVEH QSRTVLVAAQ
     QARDQAW
//