ID A0A0N0AN87_9ACTN Unreviewed; 731 AA.
AC A0A0N0AN87;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Kinase {ECO:0000313|EMBL:KOX16390.1};
GN ORFNames=ADL06_33560 {ECO:0000313|EMBL:KOX16390.1};
OS Streptomyces sp. NRRL F-6491.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1519495 {ECO:0000313|EMBL:KOX16390.1, ECO:0000313|Proteomes:UP000037743};
RN [1] {ECO:0000313|EMBL:KOX16390.1, ECO:0000313|Proteomes:UP000037743}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL F-6491 {ECO:0000313|EMBL:KOX16390.1,
RC ECO:0000313|Proteomes:UP000037743};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Purine metabolism. {ECO:0000256|ARBA:ARBA00025704}.
CC -!- SIMILARITY: Belongs to the RelA/SpoT family.
CC {ECO:0000256|ARBA:ARBA00007476}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOX16390.1}.
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DR EMBL; LGEE01000278; KOX16390.1; -; Genomic_DNA.
DR RefSeq; WP_053646942.1; NZ_LGEE01000278.1.
DR AlphaFoldDB; A0A0N0AN87; -.
DR PATRIC; fig|1519495.3.peg.7164; -.
DR OrthoDB; 9805041at2; -.
DR Proteomes; UP000037743; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0015969; P:guanosine tetraphosphate metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR CDD; cd05399; NT_Rel-Spo_like; 1.
DR Gene3D; 3.10.20.30; -; 1.
DR Gene3D; 3.30.70.260; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR002912; ACT_dom.
DR InterPro; IPR012675; Beta-grasp_dom_sf.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR007685; RelA_SpoT.
DR InterPro; IPR004095; TGS.
DR InterPro; IPR012676; TGS-like.
DR PANTHER; PTHR21262:SF31; BIFUNCTIONAL (P)PPGPP SYNTHASE_HYDROLASE SPOT; 1.
DR PANTHER; PTHR21262; GUANOSINE-3',5'-BIS DIPHOSPHATE 3'-PYROPHOSPHOHYDROLASE; 1.
DR Pfam; PF13291; ACT_4; 1.
DR Pfam; PF13328; HD_4; 1.
DR Pfam; PF04607; RelA_SpoT; 1.
DR Pfam; PF02824; TGS; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00954; RelA_SpoT; 1.
DR SUPFAM; SSF55021; ACT-like; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81271; TGS-like; 1.
DR PROSITE; PS51671; ACT; 1.
DR PROSITE; PS51831; HD; 1.
DR PROSITE; PS51880; TGS; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:KOX16390.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022840};
KW Transferase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:KOX16390.1}.
FT DOMAIN 97..194
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
FT DOMAIN 445..509
FT /note="TGS"
FT /evidence="ECO:0000259|PROSITE:PS51880"
FT DOMAIN 646..720
FT /note="ACT"
FT /evidence="ECO:0000259|PROSITE:PS51671"
FT REGION 385..414
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 543..573
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 548..567
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 731 AA; 78422 MW; 7D9F5FFE23338265 CRC64;
MSAEATNPVS AADDAATDVT VRRRGRARID LRRLGRAALL GATAGPAPRD RLPDAIGHVA
EAHRAHHPEA DLTVLRRAYV LAESSHRGQF RKSGEPYITH PLAVTLILAE LGAETTTLTA
SLLHDTVEDT EVTLDQVRRE FGDEVAYLVD GVTKVEKIDY GAAAEPETFR KMLVATGNDV
RVMSIKLADR LHNMRTLGVM RPEKQARIAR VTRDVLIPLA ERLGVQALKT ELEDLVFAIL
HPEEYETTRA LIAAHPHAPD ALGAVAEQVD AVLREAGIGA EVLVRPRHFV SVHRVRLKRG
ELRGCDFGRL LVLVAEDADC YGVLGELHTC FTPVISEFKD FIAAPKFNLY QSLHTAVAAP
DGAVAEVLIR THRMHRVAEA GVVALGNPHG GQEPAEPPEG TAPEDGERVD PTRPGWLSRL
LDWQQSAPDP DTFWTSLRAD LAEDDEITVF RADGSAPGTI SLPAGASCVD AAYAQYGEAA
HSCLGARVNG RLAPLSTVLG DGDTVQLLLA QDPVSGPSPE WLDHARTPAA RIAITEWLRA
HPESAAPAAP RLPSPPQSPP PAEPRPAADR RPGAELHADL DGERPAAVRP AGCCTPVPPD
EITGFLVRGG SVTVHRSGCA SADAMRRVGR APVAVRWGDT AQGRVTLVAE SFGRPGLLAD
LTEAIAAAGA AVVSATVEPP SEQRVRHTYT LHLPDAAELP ALMRAMRDVP GVYDVSRARH
RASPRPRPRR A
//
