ID A0A0N0B293_9ACTN Unreviewed; 432 AA.
AC A0A0N0B293;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Chloride channel core {ECO:0000313|EMBL:KOX46866.1};
GN ORFNames=ADL09_16700 {ECO:0000313|EMBL:KOX46866.1};
OS Streptomyces sp. NRRL F-7442.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1519498 {ECO:0000313|EMBL:KOX46866.1, ECO:0000313|Proteomes:UP000037772};
RN [1] {ECO:0000313|EMBL:KOX46866.1, ECO:0000313|Proteomes:UP000037772}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL F-7442 {ECO:0000313|EMBL:KOX46866.1,
RC ECO:0000313|Proteomes:UP000037772};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the chloride channel (TC 2.A.49) family.
CC {ECO:0000256|ARBA:ARBA00009476}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOX46866.1}.
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DR EMBL; LGEH01000146; KOX46866.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N0B293; -.
DR PATRIC; fig|1519498.3.peg.3469; -.
DR Proteomes; UP000037772; Unassembled WGS sequence.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd00400; Voltage_gated_ClC; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF9; ION-TRANSPORT PROTEIN YFEO-RELATED; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 57..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..173
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 185..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 309..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 338..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 364..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 398..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 432 AA; 43352 MW; 20044C9022AB825C CRC64;
MRQTLLSPGY RRLLLLCVLL GVPVSLACFF FVGFQHELQH WVWTSLPEAV GYDTPPWWWP
LPALVLAGLV LAPIVTRMPG GGGHLPVDGL GGAPVGPRAL PGAVLAALAT LPLGVVLGPE
APLMAVGSGL ALLAVRRRTG VDQRASAILA TAGSTAAIST ILGGPIAAAV LLIEGAGLAG
TQLVALLLPC LLASATGALV FTGFGQWTGL KIGALSLPDL PPQAGPDAGD FLWGLPTAAL
IAVLVTLARA LGRRTVTWTR HRTAARTVAC ATAVGVCVAA YALITGRNPA EAALSGQATL
AQLAAHPHAW SVGALVALVA CKGLAWGIAL GSLRGGPIFP SVLLGAATAL ACSGLPGFGT
TPALALGISA AAAAVTGLPL GSAVLAVLLM GRDAHDQMPL IVMASVVSFV VAQLVRRDGA
GTRKAPATGA ER
//
