ID A0A0N0BDQ9_9HYME Unreviewed; 640 AA.
AC A0A0N0BDQ9;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 13-SEP-2023, entry version 20.
DE RecName: Full=guanylate cyclase {ECO:0000256|ARBA:ARBA00012202};
DE EC=4.6.1.2 {ECO:0000256|ARBA:ARBA00012202};
GN ORFNames=WN51_02520 {ECO:0000313|EMBL:KOX70464.1};
OS Melipona quadrifasciata.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC Anthophila; Apidae; Melipona.
OX NCBI_TaxID=166423 {ECO:0000313|EMBL:KOX70464.1, ECO:0000313|Proteomes:UP000053105};
RN [1] {ECO:0000313|EMBL:KOX70464.1, ECO:0000313|Proteomes:UP000053105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0111107301 {ECO:0000313|EMBL:KOX70464.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KOX70464.1};
RA Pan H., Kapheim K.;
RT "The genome of Melipona quadrifasciata.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; KQ435859; KOX70464.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N0BDQ9; -.
DR STRING; 166423.A0A0N0BDQ9; -.
DR OrthoDB; 2898719at2759; -.
DR Proteomes; UP000053105; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0004383; F:guanylate cyclase activity; IEA:UniProtKB-EC.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 6.10.250.780; -; 1.
DR Gene3D; 3.90.1520.10; H-NOX domain; 1.
DR Gene3D; 3.30.450.260; Haem NO binding associated domain; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR038158; H-NOX_domain_sf.
DR InterPro; IPR011644; Heme_NO-bd.
DR InterPro; IPR011645; HNOB_dom_associated.
DR InterPro; IPR042463; HNOB_dom_associated_sf.
DR InterPro; IPR024096; NO_sig/Golgi_transp_ligand-bd.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR PANTHER; PTHR45655; GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2; 1.
DR PANTHER; PTHR45655:SF5; SOLUBLE GUANYLATE CYCLASE 89DA-RELATED; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR Pfam; PF07700; HNOB; 1.
DR Pfam; PF07701; HNOBA; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF111126; Ligand-binding domain in the NO signalling and Golgi transport; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW Reference proteome {ECO:0000313|Proteomes:UP000053105}.
FT DOMAIN 427..553
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 640 AA; 72365 MW; 5A4F2A0668F34C43 CRC64;
MKFSLQLEYG EDVWLQLLER ADCKHMVFNT RQMYPDELMT NLAAALAEFN GESVEDVMQF
FGKCFVRFFS NLGYACMIKA TGRYFCDFLQ SVDNIHMQMR FTYPRMKSPS MYTTHVDPQG
VVLVYRSTRK GFTHYLMGQL FQIAKELYET DLIIRVLGSS NNIPGSRSVM VKFRIDFDNR
EYIAKNNSMK TPLGRELAPV SISFLLRLFP FGVVINKDMK ILGAGDKLLQ AWGGSSSILN
KHVTDVFKVR RPKGISFTWG NVMYLHSVMF ELELIRLNDN DASSNSDNTP STSSRLDRRG
SQGARSILLK GQMRYIEDLK AIIFLCSPLI NSLDELLNMG LYLNDLNPHG LSRELVLAGW
QHCGRLEMMF ERAEQRSTEL ENSYALLDRW KNKSDELLYS MIPQTVADRL RAGASPLSTC
ESFESISVLF CELCDLDYST IEGAMDIVSS MNAVYSCFDS LMDEFNVYKV ETVGRVYMAA
SGAPDRTENH AQNIADVSLQ LLKHVRSLKL PSGVDIQIRI GIHSGPAVAG VVGIKVPRYC
FFGDTVNTAS RMQTTSLRLE PIDINYLQHF HGTQPGKVHI SSDAKALLPP DRYHVESRGL
VWVKQGKGNM ETYWLSDKVA TDVKSTEQQA KPEGLLVTDV
//
