ID A0A0N0BFP0_9HYME Unreviewed; 743 AA.
AC A0A0N0BFP0;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=LIM/homeobox protein Lhx1 {ECO:0000313|EMBL:KOX73604.1};
GN ORFNames=WN51_13681 {ECO:0000313|EMBL:KOX73604.1};
OS Melipona quadrifasciata.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC Anthophila; Apidae; Melipona.
OX NCBI_TaxID=166423 {ECO:0000313|EMBL:KOX73604.1, ECO:0000313|Proteomes:UP000053105};
RN [1] {ECO:0000313|EMBL:KOX73604.1, ECO:0000313|Proteomes:UP000053105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0111107301 {ECO:0000313|EMBL:KOX73604.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KOX73604.1};
RA Pan H., Kapheim K.;
RT "The genome of Melipona quadrifasciata.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
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DR EMBL; KQ435794; KOX73604.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N0BFP0; -.
DR STRING; 166423.A0A0N0BFP0; -.
DR OrthoDB; 932158at2759; -.
DR Proteomes; UP000053105; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR CDD; cd09375; LIM2_Lhx1_Lhx5; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR049619; Lhx1/5_LIM2.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR24208:SF105; DLIM1; 1.
DR PANTHER; PTHR24208; LIM/HOMEOBOX PROTEIN LHX; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR Pfam; PF00412; LIM; 1.
DR SMART; SM00389; HOX; 1.
DR SMART; SM00132; LIM; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000053105};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 116..179
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 282..342
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 284..343
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 180..290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 407..430
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 443..509
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 529..592
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 624..654
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 180..204
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 239..263
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 409..423
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..468
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 529..562
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 563..592
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 743 AA; 80333 MW; 7124E47F8F3C8BFA CRC64;
MAKNYTYVDV WLRIDTFMRW ETWSGDAPVM CRMRETNYGS VPAECFGPSM ARRVCPLLRL
QNHVAGQVFL QGSEAVLQRG FLQPLRSSLL ARAKVAGKTK FLNVQMHSLA KVRYGTKCSG
CLQGISPQDL VRKARDKVFH LNCFTCLVCR KQMSTGEELY VLDDNKFVCK QDYLSGKPLP
DTHHVHGHHG SEDEDEDGSS HHHHGGVGGS HLGPHNLGPG GPGDQTVGHT GDLPLGSDPC
KQEDSEDQGS LDGDPETRDS QTENKSPDGG AGGGSGDGGA GSKRRGPRTT IKAKQLEILK
SAFSSTPKPT RHIREQLAKE TGLPMRVIQV WFQNKRSKER RLKQLTSMGR SPFFGGSRKM
RGFPLNLNPG ALGGEDGPPP GFPYFGAEKF EFGYGGPVAF HHEFFGAHPP PHPHGPPFSG
PGNPGLDPAS LAGMAAAVAV TGEYPPPGAG GGPPEFLTGP PGQGPPAPSS GSPGEFLAPS
GGAQGNPSAG GNGGGPGGGG GGGGFLEPHQ MQSEGLAWNV ASRISTLPER VDGVKEKRSE
RKRGVDYKPK AAGGEKDDGE GRWSVQQQQQ QQQQQPRRSS VRVNRTGRQE ANKTEMLYKT
LVKFSDGEAH LQLTATMTME LWRKRGEEEE EEEEEEEAAA SKTAKQRRKK RVRKEGRKEG
ILEGGFTAGS QVVAGYAIEK HSEIVSVAAN TGLFKLNIGI KFARFELRGK VQCSRCGAFE
SKRNVIECFI KKIEIIHVLY VVM
//
