ID   A0A0N0DBM3_FUSLA        Unreviewed;       744 AA.
AC   A0A0N0DBM3;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   13-SEP-2023, entry version 19.
DE   RecName: Full=NmrA-like domain-containing protein {ECO:0008006|Google:ProtNLM};
DE   Flags: Fragment;
GN   ORFNames=FLAG1_10225 {ECO:0000313|EMBL:KPA36984.1};
OS   Fusarium langsethiae.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX   NCBI_TaxID=179993 {ECO:0000313|EMBL:KPA36984.1, ECO:0000313|Proteomes:UP000037904};
RN   [1] {ECO:0000313|EMBL:KPA36984.1, ECO:0000313|Proteomes:UP000037904}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Fl201059 {ECO:0000313|EMBL:KPA36984.1,
RC   ECO:0000313|Proteomes:UP000037904};
RA   Lysoe E., Divon H.H., Terzi V., Orru L., Lamontanara A., Kolseth A.-K.,
RA   Frandsen R.J., Nielsen K., Thrane U.;
RT   "The draft genome sequence of Fusarium langsethiae, a T-2/HT-2 mycotoxin
RT   producer.";
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase S8 family. {ECO:0000256|PROSITE-
CC       ProRule:PRU01240}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPA36984.1}.
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DR   EMBL; JXCE01000503; KPA36984.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N0DBM3; -.
DR   OrthoDB; 1051706at2759; -.
DR   Proteomes; UP000037904; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd05259; PCBER_SDR_a; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR   Gene3D; 3.90.25.10; UDP-galactose 4-epimerase, domain 1; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR008030; NmrA-like.
DR   InterPro; IPR045312; PCBER-like.
DR   InterPro; IPR000209; Peptidase_S8/S53_dom.
DR   InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR   InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR   PANTHER; PTHR47706:SF1; CIPA-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12460)-RELATED; 1.
DR   PANTHER; PTHR47706; NMRA-LIKE FAMILY PROTEIN; 1.
DR   Pfam; PF05368; NmrA; 1.
DR   Pfam; PF00082; Peptidase_S8; 1.
DR   PRINTS; PR00723; SUBTILISIN.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   SUPFAM; SSF52743; Subtilisin-like; 1.
DR   PROSITE; PS51892; SUBTILASE; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU01240};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW   ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000037904};
KW   Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW   ProRule:PRU01240}.
FT   DOMAIN          216..422
FT                   /note="Peptidase S8/S53"
FT                   /evidence="ECO:0000259|Pfam:PF00082"
FT   DOMAIN          470..684
FT                   /note="NmrA-like"
FT                   /evidence="ECO:0000259|Pfam:PF05368"
FT   ACT_SITE        224
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT   ACT_SITE        256
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT   ACT_SITE        407
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT   NON_TER         744
FT                   /evidence="ECO:0000313|EMBL:KPA36984.1"
SQ   SEQUENCE   744 AA;  82642 MW;  9E1515F6EFEC4AB4 CRC64;
     MTVSIQTRIS HEESPLGRLF VTLANVSLIR YDKTGEEGEE CNVHFGFDER KEAECFAHYL
     KVAQENLFEK FMRGPFYDKK VVYLRNLRTS TIDETPARMQ FSIVSRDLGD SKHAYRAILT
     QDNATRCICF DFKSKPSGVK RWDLLQSRIW VYDEDANGKP YISQTDWDTL TGQSVVKSVE
     GATFVKGGHE RTTNDWLEEL DRLFRVMKPD RNDRYKKVKI AVIDSGLNDK VKSRYMAQNN
     IVYKDFTHET RNDSWHGTCC AKIICDMYEE ATLYIARIFE KDHADEKEGP IRMAKAIDWA
     ISEPNCADII SISAGFRDYS QELSNAVTRA KAAGKLVVAA AANWANTGTV AFPARHNLTT
     MCIYSTNTSN QSSSFNPEPR SDTHNFALLG EEFQHPDQKS GPMSGTSMAT AAAAGLAANI
     IDFSRQEDNK SYIWRLPDVG TLPGMLSIFS DGKGELGLYC NIKMSAFKNI AVAGAAGDLG
     SAVFNALVTS SKFNLTVLTR KGSKSTFPSG TKVIEVDYDS LDSLTAALQG QDAVVSTVGS
     LAIPIQNLLI DAAVAAGVKR FLPSEFGSNL VVPSVRKLPV FGTKVAVEDK LTELAKQGKI
     SYNFVYNGAF LDWGIKNNFF LDFSKPELTL WDQGDAEFST TTLASVGDAV VGVLTHPQET
     QDRIVYVQDT VLTQKKILEL AKEVNPGKEW KVQYAKIDDI TAQSDANVAK GIYDWPTLAP
     YLFRSLFDAK SVPKYEKLDN ELLG
//