ID   A0A0N0H116_9ACTN        Unreviewed;      1143 AA.
AC   A0A0N0H116;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Alpha-mannosidase {ECO:0000313|EMBL:KPC64102.1};
GN   ORFNames=ADL29_13855 {ECO:0000313|EMBL:KPC64102.1};
OS   Streptomyces chattanoogensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=66876 {ECO:0000313|EMBL:KPC64102.1, ECO:0000313|Proteomes:UP000037982};
RN   [1] {ECO:0000313|Proteomes:UP000037982}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL ISP-5002 {ECO:0000313|Proteomes:UP000037982};
RA   Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPC64102.1}.
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DR   EMBL; LGKG01000112; KPC64102.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N0H116; -.
DR   PATRIC; fig|66876.3.peg.3058; -.
DR   Proteomes; UP000037982; Unassembled WGS sequence.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.70.98.10; -; 1.
DR   Gene3D; 1.20.1050.60; alpha-1,2-mannosidase; 1.
DR   Gene3D; 1.20.1610.10; alpha-1,2-mannosidases domains; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.30.2080.10; GH92 mannosidase domain; 1.
DR   InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR   InterPro; IPR014718; GH-type_carb-bd.
DR   InterPro; IPR005887; GH92_a_mannosidase_put.
DR   InterPro; IPR041371; GH92_N.
DR   InterPro; IPR012939; Glyco_hydro_92.
DR   NCBIfam; TIGR01180; aman2_put; 1.
DR   PANTHER; PTHR12143; PEPTIDE N-GLYCANASE PNGASE -RELATED; 1.
DR   PANTHER; PTHR12143:SF43; PUTATIVE SUBFAMILY (AFU_ORTHOLOGUE AFUA_6G13760)-RELATED; 1.
DR   Pfam; PF07971; Glyco_hydro_92; 1.
DR   Pfam; PF17678; Glyco_hydro_92N; 1.
DR   SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000037982};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..38
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           39..1143
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5005850124"
FT   DOMAIN          279..493
FT                   /note="Glycosyl hydrolase family 92 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF17678"
FT   DOMAIN          499..999
FT                   /note="Glycosyl hydrolase family 92"
FT                   /evidence="ECO:0000259|Pfam:PF07971"
FT   REGION          38..105
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          565..586
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1003..1023
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        63..89
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        565..584
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1143 AA;  123868 MW;  8B9FBFD99450FEE7 CRC64;
     MRHRHRYRPP RPPRKFTRPA ALAAAALFVI TAHLPAQAAP AQKPPGATEF RSSFEPGDPA
     PTWSDTVDTT PDGTPRASGV TQETTPARPG MTSHPDAGPT DSPTAKAHAG FTGTHALRYG
     GTHTGPARGY SYNRLFDVDI RITASTSLSY KLFPEMARTD LSYPATHVAV DLAFTDGTYL
     SDLHAVDQHG APLTPQGQAA SKTLYANQWN NREARIGAVA AGKTVDRILI AYDAPRAPRT
     APTFRGWVDD ITLAPSPPDR RLRHLSDYAL TTRGTLSSGS FSRGNTFPAT AVPNGFNFWT
     PVTNAGSADW LYEYARRNNA DNLPALQAFS ASHEPSPWMG DRQTFQVMPT IAPGTPDASR
     TARALPFHHS RETARPHYYG VTFDNGLKAE ITPTDHAALM RFTFPGSNAG LIFDNVDNRG
     GLTLDTERGI VTGFSDVKSG LSVGATRLFV YGVFDAPVTG GGKLDGGGGK DVTGYLRFRP
     GADRTVTMRI ATSLIGVDQA KANLSREIPA GAAFADVRGR AQAQWDGLLG RVEVEGASRD
     QLTTLYSNLY RLYLYPNSGS EKVGSRTRYA SPFSPQTGPD TPTRTGSKIV DGEIYVNNGF
     WDTYRTTWPA YSLLTPHRAG RMVDGFVQQY KDGGWISRWS SPGYADLMTG TSSDVAFADA
     YAKGVTFDAK TAYEAAVKNA TVAPPSPGVG RKGMSTSPFL GYTSTDTREG MSWALEGYLN
     DFGIARMGEA LYKKTHNRRY QEEATYFRHR AQNYVRLFDT RVGFFQGKDA QGKWRLAPGK
     FDPRVWGHDY TETNAWTFAF TAPQDTRGLA GLYGGRSALA RKLDAYFTTP ETAAKEFAGS
     YGDVIHEMTE ARDTRMGMYG HSNQPSHHIA YTYDAAGQPW KTQEKVREAL SRLYLGSEIG
     QGYPGDEDNG EMSAWYLFSA LGFYPLVMGQ GEYAVGSPLF TKATVHLENG HELTVNAPRN
     NARNIYVQGL KVDGKPWNST ALPHALLSRG GRLDFAMGPK PSAWGSGKNA GPTSLTHDDR
     IPTPARDLTV PGSSPLLDDT SATDAVLGAA TDLPVVSAGS HAAQYTLTSS DREKAPTGWV
     LQGSPDGAAW TDLDRRAGET FTWNHQTRVF TVAHPGTYAH YRLVPAGGST ARLAEVELLS
     AAG
//