ID A0A0N0HKD4_9ACTN Unreviewed; 360 AA.
AC A0A0N0HKD4;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Threonine aldolase {ECO:0000313|EMBL:KPC80850.1};
GN ORFNames=ADK82_18185 {ECO:0000313|EMBL:KPC80850.1};
OS Streptomyces sp. NRRL S-4.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1519471 {ECO:0000313|EMBL:KPC80850.1, ECO:0000313|Proteomes:UP000037987};
RN [1] {ECO:0000313|Proteomes:UP000037987}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL S-4 {ECO:0000313|Proteomes:UP000037987};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the threonine aldolase family.
CC {ECO:0000256|ARBA:ARBA00006966}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPC80850.1}.
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DR EMBL; LGKJ01000151; KPC80850.1; -; Genomic_DNA.
DR RefSeq; WP_053929987.1; NZ_LGKJ01000151.1.
DR AlphaFoldDB; A0A0N0HKD4; -.
DR STRING; 1519471.ADK82_18185; -.
DR PATRIC; fig|1519471.3.peg.3781; -.
DR Proteomes; UP000037987; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:UniProt.
DR CDD; cd06502; TA_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR48097; L-THREONINE ALDOLASE-RELATED; 1.
DR PANTHER; PTHR48097:SF5; LOW SPECIFICITY L-THREONINE ALDOLASE; 1.
DR Pfam; PF01212; Beta_elim_lyase; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
FT DOMAIN 22..309
FT /note="Aromatic amino acid beta-eliminating lyase/threonine
FT aldolase"
FT /evidence="ECO:0000259|Pfam:PF01212"
SQ SEQUENCE 360 AA; 39612 MW; 0555A1001982D12D CRC64;
MADPATVRTD ARRHHDPQVR GFASDNYAGA HPEVLAALAL ANGGHQVAYG EDDYTGHLQR
IMHSHFGPTA EAFPVFNGTG ANVVALQALT DRWGAVICAE SAHINVDEGG APERVGGLKL
LTVPTPDGKL TPELIDREAY GWDDEHRAMP QVVSITQNTE LGTVYTPQEI RAICDHAHGR
GMKVHLDGAR IANAAASLDV PMRTFTNTVG VDVLSFGGTK NGALFGEAVV VLNPDAVRAM
KHLRKLSMQL ASKMRFVSVQ LEALLARDLW LRNARHANAM AQRLAEGVRT VDGVEILHPV
QANAVFARLP HEVTERLQKR FRFYFWDEKA GDVRWMCAFD TREDDVDDFV LALKEEMARQ
//
