ID A0A0N0JD51_9PROT Unreviewed; 1885 AA.
AC A0A0N0JD51;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN ORFNames=IP80_08405 {ECO:0000313|EMBL:KPF48946.1};
OS beta proteobacterium AAP65.
OC Bacteria; Pseudomonadota; Betaproteobacteria.
OX NCBI_TaxID=1523424 {ECO:0000313|EMBL:KPF48946.1, ECO:0000313|Proteomes:UP000037849};
RN [1] {ECO:0000313|EMBL:KPF48946.1, ECO:0000313|Proteomes:UP000037849}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AAP65 {ECO:0000313|EMBL:KPF48946.1,
RC ECO:0000313|Proteomes:UP000037849};
RA Zeng Y., Feng F., Liu Y., Koblizek M.;
RT "Novel Diversity of Limnic Aerobic Anoxygenic Phototrophic Bacteria as
RT Revealed by High-throughput Strain Identification and Genome Sequencing.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPF48946.1}.
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DR EMBL; LJHW01000012; KPF48946.1; -; Genomic_DNA.
DR STRING; 1523424.IP80_08405; -.
DR PATRIC; fig|1523424.3.peg.280; -.
DR OrthoDB; 9809851at2; -.
DR Proteomes; UP000037849; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 3.30.190.20; -; 1.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 3.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR041102; UvrA_inter.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR Pfam; PF17760; UvrA_inter; 1.
DR SMART; SM00382; AAA; 4.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 3.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000037849};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 26..581
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 648..974
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 1024..1499
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 1567..1848
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 1308..1336
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1308..1329
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1885 AA; 205442 MW; B76DA492ED05C0ED CRC64;
MSSSGVIRIR GARQHNLKNL DLDIQTGELT VVTGPSGSGK SSLVFDTLYA EGQRRYVETF
SAYARQFLDR MDRPAVDRVD GVPPAIAIDQ TNPVRTSRST VGTMTELNDH LKLLFARAAQ
LFDKQTALPV RHDSAESIHA DLRARAEALG DPRLVLTFPM ELPADTTAEQ QEQWLAASGF
TRVQEERVEG TRKILDVVAD RFRIAGTEKV RAMDAIELAL KRGGGRLKVH VQPAEGEAQL
WRWSTGLHCP ESDIRYADPQ PAMFSFNSAY GACETCRGFG RVIGVDMGLV IPDHRKTLRN
GAIKPMQTPA WADCQDDLVK YAGEAGIPRD TPWSQLSAAQ RDWVVEGTPN WAGNWNKQWY
GVRRFFEYLE SKAYKMHIRV LLSKYRSYTP CGACGGARLK LEPLLWRIGD KAGADAVLPA
TKRYLPVGAQ WSREQLEALP GLSLHDLMQL SIERLRRFFD SLTLPSSLLD DALKLLLDEV
RTRLKYLCDV GLGYLTLDRQ SRTLSGGEVQ RINLTTALGT SLVNTMFVLD EPSIGLHPRD
MNRIVQAMHR LRDAGNTLVV VEHDPAVMLA ADRLIDMGPG PGERGGQIVF DGTPEAARNA
NTLTGAYLGG RKQVGAGFRK LVNEATPKLI LEGAREHNLQ NVSVAFPLQR LVCVTGVSGS
GKSTLIQDVL YPALARHFGK ATETPGVHDR LLGADALADA VFVDQSPIGK TARSNPASYV
GAFDELRKIF ADAPLARERS YTAGTFSFNA GDGRCPTCGG SGFEHVEMQF LSDVYLRCQD
CDGRRYRSEI LDVRVVRGPM QLSIADVLDL TVAEAAHWFQ NDREVVARLQ PIVDVGLDYV
RLGQPVPTLS GGEAQRLKLA GFLAEAAASA SSYASSRLAK KGTLFLFDEP TTGLHFDDIA
KLMRALRKLQ DAGHSLLVIE HNLDVIRAAD WIVDLGPEGG EAGGEVVCEG TPDDVKLHPT
SHTALALRDY EQALGFGTPQ AEESRALQTV LREARRARQA MEDSIRIVNA KEHNLKSLSV
EIPRGKFNVI TGVSGSGKST LAFDILFNEG QRRYLESLNA YARSIVQPAG RPEVDAVYGI
PPTVAIEQRL SRGGRKSTVA TTTEVWHFLR LLWVKLGLQH CVHDGAPVKA QSAESIAAQL
LRDHKGEHVG LLAPLVVNRK GVYTDLAKWA KARGHSHLRV DGEFLSLSPF PRIDRFKEHT
IELPVGDLIV TPENETALRE MLSKALALGK GVLHLLHPLT GLDDSMVEGG TQGRGIGQVK
VFSTKRACPV CGTSYPELDP RMFSYNSKHG WCTGCVGTGL KLTREQRKAY DDSVRDDDNK
GREQSFPSEE PEVEGVVDEP CGDCGGARLN KASRGVTFEE RAISDIARLS VHETRAWIET
LQLTGRDADI ARDVVSEIKS RLVFLEDVGL GYLTLDRAAP TLSGGEAQRI RLAAQLGSNL
QGVCYVLDEP TIGLHPRDNG ILLNALAKLG SAGNTLVVVE HDEDTIRRAE HIIDIGPGAG
KRGGHLVAQG TAADLAAQPD SVTGRLLAHP LQHPLVARRA IDWEAPALIL RGATLHNLQR
VDLRVPLGRL VAITGVSGSG KSTLARDVLL ANVQSALTGN RKWAGCETLE GFQHIDRVLE
VDQTPIGKTP RSCPATYIGF WDAIRKLFTE TLEARARGYG TARFSFNTGD GRCPGCEGQG
MKTIEMSFLP DVKVPCDVCH GARFNPETLA VTWRGKSIGD VLQMEVDEAV VFFASMPSIA
HPLQLLKDVG LGYLTLGQPS PTLSGGEAQR IKLVTELSKV RDDVTRRGQK PPKTLYVLDE
PTVGLHMADV ERLIRVLHRL VEGGHSVVVI EHDLDVIAEA DWVVDLGPEG GTGGGRVVVA
GAPEAVVASG SHTGRALAPV LARVN
//
