ID A0A0N0MEE7_9PROT Unreviewed; 380 AA.
AC A0A0N0MEE7;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Hemolysin D {ECO:0000313|EMBL:KPH85474.1};
DE Flags: Precursor;
GN ORFNames=GLUCOINTEAF2_0203354 {ECO:0000313|EMBL:KPH85474.1};
OS Komagataeibacter intermedius AF2.
OG Plasmid unnamed 2 {ECO:0000313|EMBL:KPH85474.1}.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Komagataeibacter.
OX NCBI_TaxID=1458464 {ECO:0000313|EMBL:KPH85474.1, ECO:0000313|Proteomes:UP000031553};
RN [1] {ECO:0000313|EMBL:KPH85474.1, ECO:0000313|Proteomes:UP000031553}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF2 {ECO:0000313|EMBL:KPH85474.1,
RC ECO:0000313|Proteomes:UP000031553};
RC PLASMID=unnamed 2 {ECO:0000313|EMBL:KPH85474.1};
RA Santos R.A., Berretta A.A., Barud H.S., Ribeiro S.J., Gonzalez-Garcia L.N.,
RA Zucchi T.D., Goldman G.H., Riano-Pachon D.M.;
RT "Draft Genome Sequence of Komagataeibacter intermedius Strain AF2, Isolated
RT from Kombucha Tea.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004519}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004519}. Membrane
CC {ECO:0000256|ARBA:ARBA00004635}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004635}.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPH85474.1}.
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DR EMBL; JUFX02000237; KPH85474.1; -; Genomic_DNA.
DR RefSeq; WP_039736764.1; NZ_JUFX02000237.1.
DR AlphaFoldDB; A0A0N0MEE7; -.
DR OrthoDB; 9800613at2; -.
DR Proteomes; UP000031553; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30158; ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER; 1.
DR PANTHER; PTHR30158:SF3; MULTIDRUG EFFLUX PUMP SUBUNIT ACRA-RELATED; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Palmitate {ECO:0000256|ARBA:ARBA00023139};
KW Plasmid {ECO:0000313|EMBL:KPH85474.1};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..380
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005855636"
FT DOMAIN 58..288
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT DOMAIN 289..356
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
SQ SEQUENCE 380 AA; 40968 MW; 5FF93C95A64A57C5 CRC64;
MMHYSRVVAP AALILALAAC QRHAASPKLP PQPVKVVTLR AEPVEIHTML PGRTEAFEIA
QVRPQVSGVI QQRLFVEGTD VQAGQQLYQI DPRVYQAAVD SAQGQLLHAQ GNEVTTRAKL
NRYGPLLKAH AVSQQEYDDA LAAERAAQGD VLSAKGQLER ATVDLGYTHM NAPITGRIGR
SILTVGALVT ANQTNNVAIV TRLDPIYVDV NLPATELLRF RRELAQGRLT RAGDNAAAIT
ITLEDGTTYE HSGRMEFSEV NVDEATATVV VRAVMPNPDR LLLPGMYVHA QLAEGTDPRA
LLVPQQAVQR NSHGDPQVWV VDADNRVNLR PITVSQAIGT DWLVMDGLKG GDRVVVEGLQ
KIHSGDTVTP ADVSAPAKAG
//
