ID A0A0N0MNA0_9ACTN Unreviewed; 1318 AA.
AC A0A0N0MNA0;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Type VII secretion system EccCa {ECO:0000313|EMBL:KPI00671.1};
GN ORFNames=OK074_5764 {ECO:0000313|EMBL:KPI00671.1};
OS Actinobacteria bacterium OK074.
OC Bacteria; Actinomycetota; Actinomycetes.
OX NCBI_TaxID=1592327 {ECO:0000313|EMBL:KPI00671.1, ECO:0000313|Proteomes:UP000037991};
RN [1] {ECO:0000313|EMBL:KPI00671.1, ECO:0000313|Proteomes:UP000037991}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OK074 {ECO:0000313|EMBL:KPI00671.1,
RC ECO:0000313|Proteomes:UP000037991};
RA Brown S.D., Utturkar S.M., Klingeman D.M., Pelletier D.;
RT "Draft genome sequences for four actinobacteria strains OK006 OK074 OV450
RT and OV320.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPI00671.1}.
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DR EMBL; LJCV01000290; KPI00671.1; -; Genomic_DNA.
DR PATRIC; fig|1592327.3.peg.8552; -.
DR Proteomes; UP000037991; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR023836; EccCa-like_Actinobacteria.
DR InterPro; IPR023837; EccCb-like_Actinobacteria.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR03924; T7SS_EccC_a; 1.
DR NCBIfam; TIGR03925; T7SS_EccC_b; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR PANTHER; PTHR22683:SF1; TYPE VII SECRETION SYSTEM PROTEIN ESSC; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 3.
DR SMART; SM00382; AAA; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR PROSITE; PS50901; FTSK; 3.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Reference proteome {ECO:0000313|Proteomes:UP000037991};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 41..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 67..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 455..655
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT DOMAIN 812..1004
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT DOMAIN 1100..1283
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT BINDING 478..485
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
FT BINDING 831..838
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
FT BINDING 1117..1124
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 1318 AA; 144259 MW; D2E260CEE483459B CRC64;
MSASVSVVII KRPPRIVPPV VPDGEVRLET PPEIPREGEE SMLMTLLPMM GMLGSVGFFF
MPNLPSYMRV VGGLMLASTL AMAIAQFAKS RQGGGAGMAQ DRRDYFRYLE QVRKDVHKTA
ELQRRSQLFQ HPDPEQLWAV AADGKRLWER RPTDADFASV RIGRGVQQLN TPLVAPETAP
KEELEPLTAA AMKAFLDAHG SLHDLPVSVS LRAFYHMTVC GDRDTVYGNA RAALCQLATL
HAPEDLMVAV VAHPSAAPDW DWIKWLPHSQ HPKAKDGAGS TRLLFDDLGE LEEALADQLD
DRPRWNRDAN PVYDQPHLIV VLDGGTVPPD SELASAEGLQ GVTFLEIAPG ELEEELRAGL
TAYVKPDRMR LFVGHESAYT GRPDVLNAAQ AQSLARQLAP FRVGSAEEGE PLLSNLDFTD
LMGIGDAGTV DVSRTWRPRT LHERLRVPIG VGESGEPVML DLKEASQEGM GPHGLCVGAT
GSGKSEVLRT LVLGLAVTHS SETLNFILAD FKGGATFAGM ADMPHTAAVI TNLADDLTLV
DRMRDSIMGE TQRRQELLRT AGNYANLHDY EKARAAGAAL EPMASLVIVL DEFSELLTAK
PDFIDMFIQI GRIGRSLGVH LLLASQRLEE GKLRGLDTYL SYRIGLRTFS AAESRTAIGV
PDAYHLPSIP GSGYLRYDTD TMVRFKAAYV SGPYHGEGPS RVHRSTQLRP ALFTAEHVAL
PPQPVIEEPE PDNRVDDALA DTVLDVIVGR MVNQGPPAHQ VWLPPLEEAP SLEQLLPQLA
VTRERGLTAP DYTALGRLNV PVGLVDKPFE QRRDVLYRDF SGGAGHGLFV GGPQSGKSTL
LRSLISSFAL THTPAEVQFY CLDFGGGSLI SMEDLAHVGG VANRLDAEKV RRTVSEVEGI
LNAREEYFRA NNVDSIQTYR QRRAAGQLPD QHWGDVFLVV DGWATFKTDY EQLEPTVTEI
ATRGLGFGVH VILAASRYTE VRPALKDMLQ NRIELRLGDP TESEIDRKVA QNVPASVPGR
GLTQDKLHFM TALPRVDGSS ATEDLSEATS ILIRGINDNW QGSRAPSVRL LPKMLASDRL
PKGFEHPERG VAVGIDESSL APVFVDFETD PHFIVFGESE SGKSAVLRLL IKQITERYTP
DQAKIVMGDY RRAHLQGVPE THLSRYCASA PALSETLEGL AGSLSRRMPG PDVTPEQLRN
RSWYSSPDAF VIIDDYDLVA TGMNPLAPLL EYLPFARDVG LRVIIARASG GASRSLYEPV
MQRMRELGAQ GLVLSGDRSE GALLGNISPS QLPPGRGYFH TRRRGGQLIQ TGWLPARF
//
