ID A0A0N0NKR1_9EURO Unreviewed; 470 AA.
AC A0A0N0NKR1;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Aldehyde dehydrogenase {ECO:0000313|EMBL:KPI38129.1};
GN ORFNames=AB675_1150 {ECO:0000313|EMBL:KPI38129.1};
OS Phialophora attinorum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Phialophora.
OX NCBI_TaxID=1664694 {ECO:0000313|EMBL:KPI38129.1, ECO:0000313|Proteomes:UP000038010};
RN [1] {ECO:0000313|EMBL:KPI38129.1, ECO:0000313|Proteomes:UP000038010}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 131958 {ECO:0000313|EMBL:KPI38129.1,
RC ECO:0000313|Proteomes:UP000038010};
RA Moreno L.F., Stielow B.J., de Hoog S., Vicente V.A., Weiss V.A.,
RA de Vries M., Cruz L.M., Souza E.M.;
RT "Draft genome of the ant-associated black yeast Phialophora attae CBS
RT 131958.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=an aldehyde + H2O + NAD(+) = a carboxylate + 2 H(+) + NADH;
CC Xref=Rhea:RHEA:16185, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:17478, ChEBI:CHEBI:29067, ChEBI:CHEBI:57540,
CC ChEBI:CHEBI:57945; EC=1.2.1.3;
CC Evidence={ECO:0000256|ARBA:ARBA00024149};
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPI38129.1}.
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DR EMBL; LFJN01000020; KPI38129.1; -; Genomic_DNA.
DR RefSeq; XP_017998092.1; XM_018140364.1.
DR AlphaFoldDB; A0A0N0NKR1; -.
DR STRING; 1664694.A0A0N0NKR1; -.
DR GeneID; 28732234; -.
DR OrthoDB; 178592at2759; -.
DR Proteomes; UP000038010; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd07102; ALDH_EDX86601; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000038010}.
FT DOMAIN 4..463
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 236
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 470 AA; 50989 MW; 066BD036658333A0 CRC64;
MSTENITTIS PSTNKPVLTR EGLSADGLLQ VGEAAQKAFK AFRKSHPTLE SRQTIVKKAL
EILESRQDAL AKEITEQMGR PIAYTSKEIA TALLRARYML RIAPEALAPT PGDSETNFKR
YIEKLPVGVV LVIFAWNYPY LILVNSLIPC ILAGDAVILK PSPQTPTIAE HMAEIFKEAG
LPERVIQYVH CGTPTDLEPL ILSPNVNHVT FTGGVAGGLA VQKIAASRID LSVGLELGGK
DPSYVRADVD PAWAADEIVD GAVFNSGQSC CSIERVYVHE KVYDAFVSEV QKVLAGYKLG
DPSSKDTNIG PVVSTRAKEA ILKQVADAKA AGAKDETPEN STFKNLPTEG NYVAPVLLTG
VDHSMAVMKD ETFGPVVPIM KVSSDEEAID LMNDSQFGLT ATIWTKDVPR GEELADQVEA
GTVFVNRADY PSPDLAWTGW KESGKGVSMG RFGFEQFVKL RSVHIKNYPK
//
