ID A0A0N0RHU0_9MICO Unreviewed; 611 AA.
AC A0A0N0RHU0;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Proposed peptidoglycan lipid II flippase MurJ {ECO:0000313|EMBL:GAP79400.1};
GN ORFNames=Y09_2242 {ECO:0000313|EMBL:GAP79400.1};
OS Brachybacterium sp. SW0106-09.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Dermabacteraceae;
OC Brachybacterium.
OX NCBI_TaxID=1704590 {ECO:0000313|EMBL:GAP79400.1, ECO:0000313|Proteomes:UP000037781};
RN [1] {ECO:0000313|EMBL:GAP79400.1, ECO:0000313|Proteomes:UP000037781}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SW0106-09 {ECO:0000313|EMBL:GAP79400.1,
RC ECO:0000313|Proteomes:UP000037781};
RA Qin Q.L., Li Y., Zhang Y.Z.;
RT "Genome Sequencing of Brachybacterium sp. SW0106-09.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAP79400.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BCAK01000023; GAP79400.1; -; Genomic_DNA.
DR RefSeq; WP_053917748.1; NZ_BCAK01000023.1.
DR AlphaFoldDB; A0A0N0RHU0; -.
DR Proteomes; UP000037781; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR InterPro; IPR004268; MurJ.
DR PANTHER; PTHR47019; LIPID II FLIPPASE MURJ; 1.
DR PANTHER; PTHR47019:SF1; LIPID II FLIPPASE MURJ; 1.
DR Pfam; PF03023; MurJ; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell shape {ECO:0000256|ARBA:ARBA00022960};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Peptidoglycan synthesis {ECO:0000256|ARBA:ARBA00022984};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 321..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 365..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..419
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 439..460
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 472..492
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 504..522
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 543..564
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 576..595
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 98..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 126..148
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 611 AA; 61716 MW; 31634F8CE1AF31E1 CRC64;
MNGTDTALEA RPAPSPRSGR IARSVLRGAG IILIVTVFAR IAGFVRYLVF GASVGAGDVG
TAYTTANMLP NVLFEIVAGG ALAAAVVPLI AGLVPERDPE ETVGTADVPV PAPAAGTTAV
PEPSTATPEP TTPAPASPPS PQSASSPDSP TRPVPAGAAL ADRIVSALLT WTVIGTLLLA
ALVIALAEPL SQLLLASDQT GAAGVGLGAT LLRIFAVQLP FYGISVVLAA YLQARRRFLW
PAMMPLLSSL VVMASYRVYA LLVPSVATVS TIDGAAVQWL GWGTTAGVVV MALPVAIASA
RAGLRVRPAL TMPAAHARRA LALGGAGLGA VGAQQIVLAL VMLLAMRAGG VGTLPVFQYA
QALYLLPYAV LVVPLVTSVF PHLSELRLVG DVTGFARVAA VSVRTVIGVS VVGAAMLIAA
GPALGQFFRH IDRAEATGVG SATAGLALGL VGFAVATQCT RILSAALRAR DALMVGAVGW
GIALVALLVL VLPSPARSAA EAATAFALAI AAGMAVGGLV GLSRIWDMLE HGGHERQVRR
TALAVPVAVL VGAVPGLLLG RLLITVDTGE VLTVLYGILC GLVAAVLSAA VLGAVDRELA
VGVVRRLRRA G
//
