ID A0A0N0RS15_9BASI Unreviewed; 1179 AA.
AC A0A0N0RS15;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Solute carrier family 12 member 3 {ECO:0000313|EMBL:KOS13345.1};
GN ORFNames=Malapachy_0095 {ECO:0000313|EMBL:KOS13345.1};
OS Malassezia pachydermatis.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Malasseziomycetes; Malasseziales; Malasseziaceae; Malassezia.
OX NCBI_TaxID=77020 {ECO:0000313|EMBL:KOS13345.1, ECO:0000313|Proteomes:UP000037751};
RN [1] {ECO:0000313|EMBL:KOS13345.1, ECO:0000313|Proteomes:UP000037751}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 1879 {ECO:0000313|EMBL:KOS13345.1,
RC ECO:0000313|Proteomes:UP000037751};
RA Triana S., Ohm R., Gonzalez A., DeCock H., Restrepo S., Celis A.;
RT "Draft Genome Sequence of Malassezia furfur CBS1878 and Malassezia
RT pachydermatis CBS1879.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOS13345.1}.
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DR EMBL; LGAV01000006; KOS13345.1; -; Genomic_DNA.
DR RefSeq; XP_017990977.1; XM_018134628.1.
DR AlphaFoldDB; A0A0N0RS15; -.
DR STRING; 77020.A0A0N0RS15; -.
DR GeneID; 28726503; -.
DR VEuPathDB; FungiDB:Malapachy_0095; -.
DR OrthoDB; 5490251at2759; -.
DR Proteomes; UP000037751; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015377; F:chloride:monoatomic cation symporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR018491; SLC12_C.
DR InterPro; IPR004842; SLC12A_fam.
DR PANTHER; PTHR11827:SF72; GH08340P; 1.
DR PANTHER; PTHR11827; SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS; 1.
DR Pfam; PF00324; AA_permease; 1.
DR Pfam; PF03522; SLC12; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000037751};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 123..143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..220
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 240..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..356
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 368..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 408..433
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 484..506
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 518..538
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 544..562
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 122..602
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
FT DOMAIN 614..698
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT REGION 16..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 903..943
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1011..1088
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..80
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 903..941
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1024..1048
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1057..1072
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1073..1087
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1179 AA; 128584 MW; C90AFBCE3ADE3B36 CRC64;
MSRFISADEA DYASLQEQLL RRSTDQESDD AHADPAAVQD TSAVAAESAT PSKAPSLHRR
NSDNSQVAPP TSNATPTKKS GLPDEATAAA VLHGRSQSRA PGGLSGAPLG EPAVRKLGTW
DGVFMPVTLN VLGIILFLRF GFILGQAGLL GALLLLVISY AIDTLTVLSL NAISTNGQVR
GGGAYYLISR SLGPEFGGSI GLIFFFGQAF NAAMNILGFV ESFVGVFGES AASGLFPEGS
WFLYLYGTVV LWLCTLVCLF GSSLFTRATL LLAVILSFAV ISIPLSSFLV EPMEDAARDV
YYTGWSWMTL SENLWPHFTS GAAGSSTAPK RENWWTVFGV LFPAVCGILA GASMSGDLRK
PSKSIPKGTN WSLIFTFGLY VVTFVIMACT VSRESFYLNV SILGDVSYWP IVIVLGELAS
CGFSALMGVM ACAKVLQAIA RDDLLPFLAP FAQGTLHGDI PTYAVLFTAV LCQAVLLMDS
INLIAQFVTM TTLLTFGVLS AATMALKAGG APSFRPSFRY WNIWTAGAGT VMSLGAMILT
DAYTAAFCIA ITVILFIMIQ VFSPPKPWGD VSHNVTYHFV RKYLLRLDER KGHVKYWRPQ
ILLLANNPRT EWNLIIFCNS LKKGALYILG HVLKGEFQEC LPELRQCHLA WLKLVDVSRI
KGFVDVVIAR DEREGARNLF LSCGLGGMKP NIVVLGFPSV LQRPSELRRG PISRATQAGT
SKLSTEAAPV ASPIRCATYV GILEDALALN KALAVAYGFD AMDLPGPSKV AQYERTDSDQ
YIDLWPIQIA HNTQTDTPTW DTYTMVLQLG TILSLTGTWK RHKLRVSVFV EHPNEIDAER
TRVRTLLDNL RIPASLRVFC LSAGHVPRYD AIVQGKRALD DESSRTLKND SWWQHVCDMR
QAQEQSKLGR SEPINASSSS ASRRASTDSL SSQSARRKNT RQFGVSLPEE HLAFHYNNIR
LGLAHPRSHD LSDSDSEMDD MDDDVSLRDD LEAELASLAV DWDPKYLINP KRAQRRERER
LQGDSSVSTS YGTLSSSQRT VTPATVQTDS RRRGRKSTTS PLISSASTSP LRSPTEPPTP
RRVRTLPPPA IDPIALDHFA LSFNDLPNLA QYLILNELIR NHSSRSTSVV LTALPAPVPG
TSSNEGDSQA YLLQLRTLYG GGPPILGVHA TTLTMTMML
//
