ID A0A0N0RTP2_9HYPO Unreviewed; 2206 AA.
AC A0A0N0RTP2;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Pre-mRNA-splicing factor brr2 {ECO:0000313|EMBL:KOS20322.1};
GN ORFNames=ESCO_006110 {ECO:0000313|EMBL:KOS20322.1};
OS Escovopsis weberi.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Escovopsis.
OX NCBI_TaxID=150374 {ECO:0000313|EMBL:KOS20322.1, ECO:0000313|Proteomes:UP000053831};
RN [1] {ECO:0000313|EMBL:KOS20322.1, ECO:0000313|Proteomes:UP000053831}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA de Man T.J., Stajich J.E., Kubicek C.P., Chenthamara K., Atanasova L.,
RA Druzhinina I.S., Birnbaum S., Barribeau S.M., Teiling C., Suen G.,
RA Currie C., Gerardo N.M.;
RT "The genome of the fungus Escovopsis weberi, a specialized disease agent of
RT ant agriculture.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOS20322.1}.
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DR EMBL; LGSR01000018; KOS20322.1; -; Genomic_DNA.
DR STRING; 150374.A0A0N0RTP2; -.
DR OrthoDB; 57056at2759; -.
DR Proteomes; UP000053831; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProt.
DR CDD; cd18019; DEXHc_Brr2_1; 1.
DR CDD; cd18021; DEXHc_Brr2_2; 1.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 2.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041094; Brr2_helicase_PWI.
DR InterPro; IPR048863; BRR2_plug.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47961; DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED; 1.
DR PANTHER; PTHR47961:SF4; U5 SMALL NUCLEAR RIBONUCLEOPROTEIN HELICASE; 1.
DR Pfam; PF21188; BRR2_plug; 1.
DR Pfam; PF00270; DEAD; 2.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF18149; Helicase_PWI; 1.
DR Pfam; PF02889; Sec63; 2.
DR PIRSF; PIRSF039073; BRR2; 1.
DR SMART; SM00382; AAA; 2.
DR SMART; SM00487; DEXDc; 2.
DR SMART; SM00490; HELICc; 2.
DR SMART; SM00973; Sec63; 2.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 2.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000053831}.
FT DOMAIN 537..721
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 756..968
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1388..1564
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT REGION 30..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 195..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 237..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..69
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 237..257
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2206 AA; 249972 MW; 28EE2EB3A72A95CD CRC64;
MSDPHRDVSQ YKYSAMSNLV LQADRRFVTR RTDEATGDPE SLAGRLSIKD MGSRVARDEA
PKQKKQPGLP DIERGSLQEG QDVLLREQRK QKSAQQTGVL GANDALIEGI TYRPRTAATR
ATFDLILTIV ATNLGDVPHE VVRSAADAAL EYLKDDDMKD IEKKKEIDEI LGTALSPKQF
NELVNLGKKI TDYDAQDDEE DVNMGENGGD DAEIDERQGV AVAFDEDEDE EDAIVDQVRD
ESSEDEDEAD QDGEAADGED AAATAAAAAA DDNDEMILDS APSGDKKKVK EKIMIPARDI
DAFWLQRQIG VFYPDAHEQT DKTKDALHIL SGEPDEAGGE EKSLREIEND LMELFDLEHH
ELVQKLVENR EKVYWLTKLA RAEDAEQRAH VEREMASEGL QGILNELRGK GSSDHDKKRK
MDIKMDIDVP ASFNTDGPKT ERPEGQLVGG LQPKRLINLE NLMFDQGNHL MTNPKVRLPE
GSTKRTFKGY EEIHVPPPKK RNDPDDVLIP ISDMPEWSRQ PFSTAKSLNK IQSKCYPTAF
EDDGNMLVCA PTGSGKTNVA MLTILREIGK HRNPETGEID LDSFKIVYIA PLKALVQEQV
GNFGKRLESY GIRVNELTGD RQLTKQQISE TQIIVTTPEK WDVITRKATD LTYTNLVRLI
IIDEIHLLHD DRGPVLESIV SRTIRKTEQT GEHVRIVGLS ATLPNYRDVA GFLRVDPKTA
LFHFDGSFRP CPLRQEFIGV TDRKAIKQLK TMNDVTYQKV IEHVGTNRNQ MLIFVHSRKE
TAKTARYIRD KALELDTINQ ILRHDAGSRE VLNEAASQAT DQDLKDILPY GFGIHHAGMN
RIDRTDVEDL FARGAIQVLV CTATLAWGVN LPAHTVIIKG TQVYSPEKGS WVELSPQDVL
QMLGRAGRPQ FDTYGEGIII TTQSEIQYYL SLLNQQLPIE SQFVSKLVDN LNAEVVLGNV
RTRDEGVEWL GYTYLFVRML RSPGLYQVGA EYEDDEALEQ KRVDLIHSAA MALRKSNLVK
YDEKTGKIQS TELGRIASHY YITASSMDTY NNLIQPSINT IELFRIFALS AEFKYIPVRQ
DEKLELAKLL GRVPIPVKES IEEPHAKINV LLQAYISRLK LDGLALMADM VYVTQSAGRI
LRAIFEIALK KGWSSVARIA LDLCKMAEKR MWPTMSPLRQ FPSCPRDVVQ KAERIDVSWS
SYFDLDPPRM GELLGMPRAG RTVCQLVSKF PRVDIQAQVQ PMTRSMLKVE LSITPNFEWD
DSIHGAAESF WIIVEDCDGE DILYHDTFLL RKDYAQSEAN EHIVDFTVPI TDPMPPNYFV
TVISDRWMHA ETKLAIPFHK LILPEKFPPH TELLDLQPLP VSALKVQSYI NLYPEWKQFN
KIQTQTFNSL YKTDQNVFVG APTGSGKTVC AEFALLRHWT QSDSGRAVYI APFQELVDAR
LHDWQKRLGP LNGGKEIVKL TGETAADLKL LEQGDLILAT PTQWDVLSRQ WKRRKNVQTV
ELFIADDVHL LGGHQGYIYE IIVSRMHYIR TQTELPMRIV ALSVSLANAR DIGEWIDAKK
HDIYNFSPHV RPVPLELHVQ SYSTPHFPSM MLAMAKPAYL AITQMSPDKP AMIFVASRKQ
TRVTARDLLA ACVMDDDEDR FLHAEVEQMK PLLDRVHEEA LAEALSHGIG YYHEALSQND
KRIVKHLYDN GAIQVLVASR DVCWELTSTA HIVIVMGTQY FEGREHRYVD YPLSEILQMF
GKALRPSKDG RGRGVLMLPQ AKREYYKKFL NEALPVESHL HNYLHDAFVT EISTKMIESG
DDAINWTTFT YFYRRLLGNP SYYSLTSTTH EGLSSYMSDL VETTLRELSE SSIIEFDEDD
GSVAPQNAAM IAAYYNISYI TMQTFLLSLN TRTKLKGILE IVTSATEFES IQIRRHEDNL
LRRIYDRVPV KMSQPAYDSP HFKVFVLLQA HFSRMQLPID LAKDQEVLLS RVLSLLSAMV
DILSSDGHLN AMNAMEMSQM VVQAMWDKDS PLKQIPHFSP EIVKVANDFG IKDIFDFMEG
MNPDENPEYK NLVQRLGLSQ KQLAQAAAFT NDKYPDLEFE HEVLDEDEIQ AGEPAYLNIK
LTRNIEEDDE VDSTVHAPFY PTKKMENWWL VVGDDKARNL LAIKRVTIGR ELSVKLEYTV
PTPGQHSLKL LLMSDSYVGV DQEREFSVTA TESMEVDEDD EDDDDE
//
