ID A0A0N0SXD0_9ACTN Unreviewed; 351 AA.
AC A0A0N0SXD0;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:KOV59232.1};
GN ORFNames=ADK64_34410 {ECO:0000313|EMBL:KOV59232.1};
OS Streptomyces sp. MMG1121.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415544 {ECO:0000313|EMBL:KOV59232.1, ECO:0000313|Proteomes:UP000037687};
RN [1] {ECO:0000313|Proteomes:UP000037687}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMG1121 {ECO:0000313|Proteomes:UP000037687};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOV59232.1}.
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DR EMBL; LGDV01000226; KOV59232.1; -; Genomic_DNA.
DR RefSeq; WP_053665554.1; NZ_LGDV01000226.1.
DR AlphaFoldDB; A0A0N0SXD0; -.
DR STRING; 1415544.ADK64_34410; -.
DR PATRIC; fig|1415544.3.peg.7442; -.
DR OrthoDB; 4268837at2; -.
DR Proteomes; UP000037687; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000037687};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 14..68
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 351 AA; 37491 MW; 57043850902175D7 CRC64;
MASHGARGRS GGRPTLEEVA ARAGVGRGTV SRVINGSPRV SDATRAAVEA AVAELGYVPN
TAARALAANR TDAIALVVPE PETRFFAEPY FSDMLRGVGA ELADTEMQLL LIFAGNDRER
RRLAQYLAAH RVDGVLLVSV HADDPLPDLL AQLEIPAVIS GPRSAGETLT SVDSDNYGGA
RSAVEHLLAR GRTRIAHITG RLDVYGAQCR VDGYRDALRD AGHPADELLV EPGDFTEEGG
RRAMSVLLDR HPGLDAVFAG SDVMAAGARQ VLREAGRRIP EDVALIGYDD SAIARHMDPP
LTSVRQPIEE MGRAMLGLLL TEIADRRPAA SRGLERRHAV LPTKLVTRAS S
//
