ID A0A0N0SZP7_9ACTN Unreviewed; 342 AA.
AC A0A0N0SZP7;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=NADP-dependent oxidoreductase {ECO:0000313|EMBL:KOV64398.1};
GN ORFNames=ADL01_28080 {ECO:0000313|EMBL:KOV64398.1};
OS Streptomyces sp. NRRL WC-3618.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1519490 {ECO:0000313|EMBL:KOV64398.1, ECO:0000313|Proteomes:UP000037738};
RN [1] {ECO:0000313|EMBL:KOV64398.1, ECO:0000313|Proteomes:UP000037738}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL WC-3618 {ECO:0000313|EMBL:KOV64398.1,
RC ECO:0000313|Proteomes:UP000037738};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOV64398.1}.
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DR EMBL; LGDW01000415; KOV64398.1; -; Genomic_DNA.
DR RefSeq; WP_053744775.1; NZ_LGDW01000415.1.
DR AlphaFoldDB; A0A0N0SZP7; -.
DR PATRIC; fig|1519490.3.peg.6128; -.
DR OrthoDB; 9805663at2; -.
DR Proteomes; UP000037738; Unassembled WGS sequence.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05288; PGDH; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR041694; ADH_N_2.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR045010; MDR_fam.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43205; PROSTAGLANDIN REDUCTASE; 1.
DR PANTHER; PTHR43205:SF7; PROSTAGLANDIN REDUCTASE 1; 1.
DR Pfam; PF16884; ADH_N_2; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000037738}.
FT DOMAIN 27..340
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 342 AA; 36359 MW; 2609ABB669948DC7 CRC64;
MSETPTPALP AVSREWHLLS RPVGWPKAED FALVEAEVPQ PREGQVLVRN LYVSVDPYMR
GRMSDAKSYV APFELGKVMQ GGAVGVVVAS NAEGLSVGDH VLHFLGWREY AAVNAKDAVK
VDPEAAPLST YLGVLGMTGL TAYAGLLRTA SFKEGDVVFV SGAAGAVGGQ VGQIAKLKGA
SRVIGSAGSD EKVKLLVEEY GFDAAFNYKD GSVASQLRDA APDGIDVYFD NVGGDHVEAA
IGALKHAGRI AICGMISVYN NTEPAPGPKN LARLIATRGR IEGLLVGDHY DLQPQFVEEV
GGWVRSGELK YRETVLEGIE NNLEAFLGVL RGDNTGKMIV KF
//
