ID A0A0N0T1C6_9ACTN Unreviewed; 485 AA.
AC A0A0N0T1C6;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Aldehyde dehydrogenase {ECO:0000313|EMBL:KOV67132.1};
GN ORFNames=ADL01_24955 {ECO:0000313|EMBL:KOV67132.1};
OS Streptomyces sp. NRRL WC-3618.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1519490 {ECO:0000313|EMBL:KOV67132.1, ECO:0000313|Proteomes:UP000037738};
RN [1] {ECO:0000313|EMBL:KOV67132.1, ECO:0000313|Proteomes:UP000037738}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL WC-3618 {ECO:0000313|EMBL:KOV67132.1,
RC ECO:0000313|Proteomes:UP000037738};
RA Noorani M.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOV67132.1}.
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DR EMBL; LGDW01000336; KOV67132.1; -; Genomic_DNA.
DR RefSeq; WP_053744235.1; NZ_LGDW01000336.1.
DR AlphaFoldDB; A0A0N0T1C6; -.
DR PATRIC; fig|1519490.3.peg.5449; -.
DR OrthoDB; 6882680at2; -.
DR Proteomes; UP000037738; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd07139; ALDH_AldA-Rv0768; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR42804; ALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR42804:SF1; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000037738}.
FT DOMAIN 24..477
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 253
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 485 AA; 51873 MW; 8782B84E75C67843 CRC64;
MTELVEHGQL FIGGELTDPL GKDVIEVISP HTEEVFGRVP HASPADVDRA VAAARTAFDE
GPWPRMTLDE RIAVVTRIKD GIAARYEEIG RVISSENGSP YSWSILAQAL GAMMVWDAAI
TVARDFTYEE SRDGALGRIL VRREPVGVVA AVAPWNVPQF VAAAKLAPAL LAGCTVILKP
SPESPLDAYI LAEITKEAGL PPGVLSILPA DREVSEYLVG HPGVDKISFT GSVAAGKRVM
EVASRQLTRV TLELGGKSAA VVLPDADLDT AVPGIVSAAW MNNGQACVAQ TRILLPRSRY
DEFADAFTQA ASALVVGDPL DPATQVGPLV AKRQQQRNLD YIRIGQEEGA KILTGGGRPA
GLDRGWYVEP TLFGDVDNSM RIAREEIFGP VICLIPYGDE SDAVKIANDS DYGLSGSVWT
ADVAHGIEVA RQVRTGTYSV NTFSLDMLGP FGGYKNSGLG REFGPEGFGE YLEHKMIHLP
AGWEG
//
