ID   A0A0N0T7P5_9NOCA        Unreviewed;       762 AA.
AC   A0A0N0T7P5;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   RecName: Full=Molybdopterin oxidoreductase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=ADL03_23320 {ECO:0000313|EMBL:KOV82706.1};
OS   Nocardia sp. NRRL S-836.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC   Nocardia.
OX   NCBI_TaxID=1519492 {ECO:0000313|EMBL:KOV82706.1, ECO:0000313|Proteomes:UP000037746};
RN   [1] {ECO:0000313|Proteomes:UP000037746}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL S-836 {ECO:0000313|Proteomes:UP000037746};
RA   Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mo-bis(molybdopterin guanine dinucleotide);
CC         Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
CC   -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC       oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOV82706.1}.
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DR   EMBL; LGDY01000104; KOV82706.1; -; Genomic_DNA.
DR   RefSeq; WP_053735630.1; NZ_LGDY01000104.1.
DR   AlphaFoldDB; A0A0N0T7P5; -.
DR   STRING; 1519492.ADL03_23320; -.
DR   PATRIC; fig|1519492.3.peg.5001; -.
DR   OrthoDB; 5287431at2; -.
DR   Proteomes; UP000037746; Unassembled WGS sequence.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:InterPro.
DR   GO; GO:0030151; F:molybdenum ion binding; IEA:InterPro.
DR   GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR   CDD; cd02787; MopB_CT_ydeP; 1.
DR   CDD; cd02767; MopB_ydeP; 1.
DR   Gene3D; 2.40.40.20; -; 1.
DR   Gene3D; 3.40.50.740; -; 1.
DR   Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR   InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR   InterPro; IPR037951; MopB_CT_YdeP.
DR   InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR   InterPro; IPR006656; Mopterin_OxRdtase.
DR   InterPro; IPR010046; Mopterin_OxRdtse_a_bac.
DR   InterPro; IPR041953; YdeP_MopB.
DR   NCBIfam; TIGR01701; Fdhalpha-like; 1.
DR   PANTHER; PTHR43105:SF4; PROTEIN YDEP; 1.
DR   PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR   Pfam; PF00384; Molybdopterin; 1.
DR   Pfam; PF01568; Molydop_binding; 1.
DR   PIRSF; PIRSF000144; CbbBc; 1.
DR   SUPFAM; SSF50692; ADC-like; 1.
DR   SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000037746}.
FT   DOMAIN          121..495
FT                   /note="Molybdopterin oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF00384"
FT   DOMAIN          643..754
FT                   /note="Molybdopterin dinucleotide-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01568"
SQ   SEQUENCE   762 AA;  83726 MW;  B5759F2EA276B4CA CRC64;
     MSSKPPQHDV DESELEVSTP KTWAAGVPGV LVSLDRAVEQ MGVTRTVKTL RLLNQREGFD
     CPGCAWPEPQ GHRKMAEFCE NGAKAVAEEA TKRRIGPEFF AEHPISSLRT KTDYWLGQQG
     RITEPMVLRP GATHYTPIGW DAAFTLIAQE LTALSSPDEA IFYTSGRTSN EAAFLYQLLV
     RSFGTNNLPD CSNMCHESSG SALNETIGIG KGSVSIKDFD LADLIVVIGQ NPGTNHPRML
     SALEDAKKNG AKIIAINPLP EAGLMRFKNP QNVAGVVGRG TALCDEFVQI KVGGDQALFQ
     AVGHLLLRWD KLDRTFIEAK THGFEQYAAS VRELDWDRVL AATGLTREQI TRVAGMFVDS
     QRTIACWAMG LTQHKHSVPT IREITNVMFL RGMIGKPGAG LCPVRGHSNV QGDRTMGIYE
     KMPEKFLLAL ENEFGIPVPR KHGFDTVDAI NAMRQGRGKV FIAMGGNFVS ATPDTPVTEK
     ALEQCSLTVH VSTKLNRSHV VHGRTALILP ALGRTESDVQ HSGEQFVTVE DSMSVVHRSR
     GRLKPASDQL LSEVSIICRL AREVLGPAHP VAWEDFEKDY DVIREHIARV VPGCTDYNTR
     VRQPDGFVLP HPPRDSQEFA TATGKANFTA NELTVIEVPE GRLLMQTLRS HDQYNTTIYG
     LDDRYRGVKD GRRVVFVNPD DLKALGLSDG QLVDIVSEWK DDPTGVVERR AESFRIVSYS
     TARGCVATYF PEANPLVPLD SKADISGTPT SKSVIVRLEP AA
//