ID   A0A0N0TS08_9PSEU        Unreviewed;       525 AA.
AC   A0A0N0TS08;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=D-alanine glycine permease {ECO:0000313|EMBL:KOX23673.1};
GN   ORFNames=ADK67_19990 {ECO:0000313|EMBL:KOX23673.1};
OS   Saccharothrix sp. NRRL B-16348.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Saccharothrix.
OX   NCBI_TaxID=1415542 {ECO:0000313|EMBL:KOX23673.1, ECO:0000313|Proteomes:UP000037722};
RN   [1] {ECO:0000313|EMBL:KOX23673.1, ECO:0000313|Proteomes:UP000037722}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL B-16348 {ECO:0000313|EMBL:KOX23673.1,
RC   ECO:0000313|Proteomes:UP000037722};
RA   Noorani M.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC       ECO:0000256|RuleBase:RU363064}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOX23673.1}.
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DR   EMBL; LGED01000197; KOX23673.1; -; Genomic_DNA.
DR   RefSeq; WP_053717970.1; NZ_LGED01000197.1.
DR   AlphaFoldDB; A0A0N0TS08; -.
DR   STRING; 1415542.ADK67_19990; -.
DR   PATRIC; fig|1415542.3.peg.4316; -.
DR   OrthoDB; 9806926at2; -.
DR   Proteomes; UP000037722; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   NCBIfam; TIGR00835; agcS; 1.
DR   PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR   PANTHER; PTHR30330:SF3; TRANSCRIPTIONAL REGULATOR, LRP FAMILY-RELATED; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU363064};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW   Symport {ECO:0000256|RuleBase:RU363064};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT   TRANSMEM        54..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        194..214
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        234..257
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        269..289
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        295..319
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        352..376
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        411..434
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        455..473
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        479..498
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
SQ   SEQUENCE   525 AA;  54300 MW;  1AE9D0E692148446 CRC64;
     MTTSPPLSPP PTVLAAEGGT LSTVEEVINS AFTPVSEAVS GFIFAEVTVF GVTFPWIVGW
     LVLAAAVFTA YFGVIQLRGF GTALRIVRGK HSKPDDPGEI SHFQALSSAV SGTVGLGNIA
     GVGVAVTIGG AGATFWMIVC GLLGMCTKFV ECTLGVKYRD VHEDGSVSGG PMHYLRKGLA
     ERFPGTAGRG VGRVLAAGAA IMILFFGIAG GNMFQANQTF AQLRSVTGGP EGFLGGDGAA
     LVFGIVLALV VGAVIIGGIK SIGRVTGKLV PAMAILYVSA CLIVILLNIT TIPAAVGQIV
     SGAFGADSVA GGAVGALIVG FQRAAFSNEA GLGSASIAHS AVKTRRPVTE GYVALLEPFI
     DTVVICTMTA LTIVVAQTQF WKDAQATVAA GGPRPDGVTV TSESFGTVLP WFPYVLTVAV
     VLFAVSTIIT WSYYGEKAWV YLFGKSKGSE TAYRVIFCAF TVVGSVLTLG SVLDFADAVL
     FTLALFNIIG LYLLAPVVKR ELTAFRASLA RDRADERARA TTGTE
//