ID A0A0N0XJW3_9NEIS Unreviewed; 247 AA.
AC A0A0N0XJW3;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=16S/23S rRNA (Cytidine-2'-O)-methyltransferase TlyA {ECO:0000313|EMBL:KPC53969.1};
DE EC=2.1.1.226 {ECO:0000313|EMBL:KPC53969.1};
GN Name=tlyA {ECO:0000313|EMBL:KPC53969.1};
GN ORFNames=WG78_04950 {ECO:0000313|EMBL:KPC53969.1};
OS Amantichitinum ursilacus.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
OC Chitinibacteraceae; Amantichitinum.
OX NCBI_TaxID=857265 {ECO:0000313|EMBL:KPC53969.1, ECO:0000313|Proteomes:UP000037939};
RN [1] {ECO:0000313|EMBL:KPC53969.1, ECO:0000313|Proteomes:UP000037939}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IGB-41 {ECO:0000313|EMBL:KPC53969.1,
RC ECO:0000313|Proteomes:UP000037939};
RA Kirstahler P., Guenther M., Grumaz C., Rupp S., Zibek S., Sohn K.;
RT "Draft genome sequence of the Amantichitinum ursilacus IGB-41, a new
RT chitin-degrading bacterium.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TlyA family.
CC {ECO:0000256|ARBA:ARBA00029460}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPC53969.1}.
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DR EMBL; LAQT01000003; KPC53969.1; -; Genomic_DNA.
DR RefSeq; WP_053936688.1; NZ_LAQT01000003.1.
DR AlphaFoldDB; A0A0N0XJW3; -.
DR STRING; 857265.WG78_04950; -.
DR PATRIC; fig|857265.3.peg.1014; -.
DR OrthoDB; 9784736at2; -.
DR Proteomes; UP000037939; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd00165; S4; 1.
DR Gene3D; 3.10.290.10; RNA-binding S4 domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR004538; Hemolysin_A/TlyA.
DR InterPro; IPR002877; RNA_MeTrfase_FtsJ_dom.
DR InterPro; IPR002942; S4_RNA-bd.
DR InterPro; IPR036986; S4_RNA-bd_sf.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR047048; TlyA.
DR PANTHER; PTHR32319; BACTERIAL HEMOLYSIN-LIKE PROTEIN; 1.
DR PANTHER; PTHR32319:SF0; BACTERIAL HEMOLYSIN-LIKE PROTEIN; 1.
DR Pfam; PF01728; FtsJ; 1.
DR Pfam; PF01479; S4; 1.
DR PIRSF; PIRSF005578; TlyA; 1.
DR SMART; SM00363; S4; 1.
DR SUPFAM; SSF55174; Alpha-L RNA-binding motif; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50889; S4; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:KPC53969.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000037939};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00182};
KW Transferase {ECO:0000313|EMBL:KPC53969.1}.
FT DOMAIN 2..68
FT /note="RNA-binding S4"
FT /evidence="ECO:0000259|SMART:SM00363"
SQ SEQUENCE 247 AA; 26464 MW; D14D053F126ED454 CRC64;
MQRADLLLVQ LGLAASRTAA QGLIEAGRVS ADGKPVSKAS VKLDADARIH IVPDAADRYV
SRGGLKLAGA LAQSGLDVTG WQALDVGIST GGFTDCLLQA GARCVVGVEV GHDQLHPRLL
ADPRVQQFEG INARHLQREQ IASALDGDIN LIVGDVSFIS LTLVLPQLAP LLPSGGYLLF
LIKPQFEAGP QHIGKGGIVR NADCYIEVER KIRQAASEQQ FEVLDYFTSP ITGGDGNREF
FIYARKR
//
