ID A0A0N0XUQ7_9ACTN Unreviewed; 848 AA.
AC A0A0N0XUQ7;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=ADL29_25945 {ECO:0000313|EMBL:KPC60973.1};
OS Streptomyces chattanoogensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=66876 {ECO:0000313|EMBL:KPC60973.1, ECO:0000313|Proteomes:UP000037982};
RN [1] {ECO:0000313|Proteomes:UP000037982}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL ISP-5002 {ECO:0000313|Proteomes:UP000037982};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPC60973.1}.
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DR EMBL; LGKG01000152; KPC60973.1; -; Genomic_DNA.
DR RefSeq; WP_053926002.1; NZ_LGKG01000152.1.
DR AlphaFoldDB; A0A0N0XUQ7; -.
DR PATRIC; fig|66876.3.peg.5691; -.
DR Proteomes; UP000037982; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd01987; USP_OKCHK; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 1.20.120.620; Backbone structure of the membrane domain of e. Coli histidine kinase receptor kdpd; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR038318; KdpD_sf.
DR InterPro; IPR025201; KdpD_TM.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR003852; Sig_transdc_His_kinase_KdpD_N.
DR PANTHER; PTHR45569; SENSOR PROTEIN KDPD; 1.
DR PANTHER; PTHR45569:SF1; SENSOR PROTEIN KDPD; 1.
DR Pfam; PF13493; DUF4118; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF02702; KdpD; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:KPC60973.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000037982};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 380..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 411..439
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 459..480
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 622..833
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 848 AA; 90951 MW; 3801CC53924A59AD CRC64;
MARGKLRIYL GAAPGVGKTY AMLSEAHRRV ERGTDCVVAF VEHHDRPRTE VMLHGLEQVP
RKELEYRGTS FTEMDVDAVL ERAPAVALVD ELPHTNIPGS RNAKRWQDIE ELLAAGIHVI
STCNIQHLES LGDIVESITG IRQKETVPDE VVRRADQIEL VDMSPHALRR RMAHGNIYKS
HKVDAALSNY FRPGNLTALR ELALLWVADR VDEYLQEYRS EHQVSKIWGS RERIVVGLTG
GSEGRTLIRR AARLAEKGAG GEVLAVYIAR SDGLTSGSPK ELAVQRTLIE DLGGTFHHVM
GEDIPSALLE FSRGVNATQI VLGTSRRKAW QYIFGPGVGA TVARDSGPDL DVHIVTHEEA
AKGRGLPVAR GARLGRPRII WGWLTGVAGP ALLTLPLMYV GAGLGFANDV LLFLTLTVAA
ALLGGLLPAL ASAVVGSLLL NWFFTPPVGR LTIADPKNIL ALVIFLLVAV SVASVVDVAA
RRTHQAARLR AESEILSFLA GSVLRGETTL DALLERVRET FAMDAVALLE RETETAPWTC
SGSVGDASPL SRPEDADVDM PVGDHMALAL SGRVLPAEDR RVLAAFAAQA AVVLDRQRLK
SQADHARKLA EGNRIRTALL AAVSHDLRTP LASIKASVTS LRSDDVEWSD EDRAELLAGI
EEGADRLDHL VGNLLDMSRV QTGTVTPLIR EIDLDEVVPM ALGGVPEDSV VLDIPEALPM
VAVDPGLLER SVANIVENAV KYSPDGETVL VSASTLGDRV EVRVADRGPG VPDDAKDRIF
EPFQRYGDVP RGAGVGLGLA VARGFAEAIG ATLTAEDTPG GGMTMVLTVP TAAGHLPAQP
DLPAAVTS
//
